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人工关节周围感染翻修术后患者报告的生活质量和疼痛结局:一项横断面研究

Patient-Reported Outcome on Quality of Life and Pain after Revision Arthroplasty for Periprosthetic Joint Infection: A Cross-Sectional Study.

作者信息

Zhang Chaofan, Liu Ziyu, Lin Yunzhi, Cai Yuanqing, Zhang Xuehui, Huang Zida, Huang Ying, Li Wenbo, Fang Xinyu, Zhang Wenming

机构信息

Department of Orthopaedic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China.

Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China.

出版信息

J Clin Med. 2022 Dec 2;11(23):7182. doi: 10.3390/jcm11237182.

Abstract

This study aims to explore the quality of life (QOL) and pain after revision surgery for periprosthetic joint infection (PJI) based on patients' reported outcomes. A cross-sectional questionnaire survey was conducted and 137 valid responses were included (response rate 64.0%). A total of 42 patients underwent debridement with implant retention (DAIR), 31 underwent one-stage revision, and 64 underwent two-stage revision. The average overall SF-36 score was 70.3. The DAIR group had significantly higher SF-36 than the two-stage revision group ( = 0.01). There was no significant difference between the one-stage revision group and the other two groups. A total of 74.5% of patients reported pain with an average McGill Pain Questionnaire (MPQ) score of 8.6. There was no significant difference in the MPQ scores among the three groups. Simple linear regression analyses demonstrated that higher preoperative PMN%, VAS, and shorter hospital stay were associated with pain (adjusted R = 4%, = 0.020; adjusted R = 2.1%, = 0.048; adjusted R = 2.1%, = 0.049; respectively). We concluded that the overall QOL of patients after revision surgery for PJI is generally satisfactory. Persistent pain is prevalent, but the severity was mostly mild. Preoperative PMN%, VAS, and hospital stay were associated with postoperative pain.

摘要

本研究旨在基于患者报告的结果,探讨人工关节周围感染(PJI)翻修术后的生活质量(QOL)和疼痛情况。进行了一项横断面问卷调查,纳入了137份有效回复(回复率64.0%)。共有42例患者接受了保留假体的清创术(DAIR),31例接受了一期翻修,64例接受了二期翻修。SF-36总体平均得分为70.3。DAIR组的SF-36得分显著高于二期翻修组(P = 0.01)。一期翻修组与其他两组之间无显著差异。共有74.5%的患者报告有疼痛,麦吉尔疼痛问卷(MPQ)平均得分为8.6。三组的MPQ得分无显著差异。简单线性回归分析表明,术前较高的中性粒细胞百分比(PMN%)、视觉模拟评分(VAS)以及较短的住院时间与疼痛相关(调整后R²分别为4%,P = 0.020;调整后R²为2.1%,P = 0.048;调整后R²为2.1%,P = 0.049)。我们得出结论,PJI翻修术后患者的总体生活质量总体令人满意。持续性疼痛普遍存在,但严重程度大多为轻度。术前PMN%、VAS和住院时间与术后疼痛相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f456/9741318/d8be746ee715/jcm-11-07182-g001.jpg

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