Electrical and Electronic Engineering, National University of Ireland Galway, H91 TK33 Galway, Ireland.
Translational Medical Device Lab, National University of Ireland Galway, H91 TK33 Galway, Ireland.
Sensors (Basel). 2022 Nov 30;22(23):9320. doi: 10.3390/s22239320.
Recent studies have shown that ablation techniques have the potential to eradicate adrenal adenomas while preserving the functionalities of the adrenal gland and the surrounding anatomical structures. This study explores a new microwave ablation (MWA) approach operating at 5.8 GHz and using anatomical and dielectric characteristics of the target tissue to create directional heating patterns. Numerical simulations are executed in planar and 3D adrenal models, considering two energy doses. The numerical study is refined accounting for the vaporization of the tissue water content. experimental evaluations on porcine adrenal models complete the study. The numerical and experimental results show that spherical ablation zones are able to cover the target for both energy doses considered. Nonetheless, most of the non-targeted tissues can be preserved from excessive heating when low energy level is used. Numerical models accounting for water vaporization are capable to foresee the experimental temperature values. This study shows that the proposed MWA directional approach operating at 5.8 GHz can be considered for creating effective and selective ablation zones.
最近的研究表明,消融技术有可能在保留肾上腺和周围解剖结构功能的同时消除肾上腺腺瘤。本研究探索了一种新的 5.8GHz 微波消融(MWA)方法,利用目标组织的解剖和介电特性来创建定向加热模式。在考虑两种能量剂量的情况下,在平面和 3D 肾上腺模型中进行了数值模拟。数值研究考虑了组织水分的蒸发进行了细化。在猪肾上腺模型上进行的实验评估完成了这项研究。数值和实验结果表明,对于所考虑的两种能量剂量,球形消融区都能够覆盖目标区域。然而,当使用低能级时,可以防止大多数非目标组织受到过度加热。考虑到水蒸发的数值模型能够预测实验温度值。本研究表明,所提出的 5.8GHz 工作频率的 MWA 定向方法可用于创建有效且选择性的消融区。