莫德纳信使核糖核酸-1273新冠疫苗接种后出现多发性角化棘皮瘤，经5-氟尿嘧啶治疗后痊愈：病例报告
Multiple Keratoacanthomas Following Moderna Messenger RNA-1273 COVID-19 Vaccination Resolved With 5-Fluorouracil Treatment: Case Report.
作者信息
Ahmed Fahad, Memon Nashwah, Haque Adel
机构信息
Department of Dermatology Perelman School of Medicine University of Pennsylvania Philadelphia, PA United States.
Lake Erie College of Osteopathic Medicine Bradenton, FL United States.
出版信息
JMIR Dermatol. 2022 Dec 1;5(4):e41739. doi: 10.2196/41739. eCollection 2022 Oct-Dec.
Cutaneous reactions have been commonly associated with the Moderna messenger RNA (mRNA) COVID-19 vaccine. Among the reported cutaneous side effects, there have not been any associations reported yet regarding keratoacanthoma development after COVID-19 mRNA vaccination. We report a novel case of an 86-year-old man who experienced an eruption of multiple keratoacanthomas 2 weeks after inoculation with the Moderna mRNA-1273 vaccine that resolved following treatment with intralesional 5-fluorouracil.
皮肤反应通常与莫德纳信使核糖核酸（mRNA）新冠疫苗有关。在报告的皮肤副作用中，尚未有关于新冠mRNA疫苗接种后发生角化棘皮瘤的相关报道。我们报告了一例新病例，一名86岁男性在接种莫德纳mRNA-1273疫苗后2周出现多发性角化棘皮瘤皮疹，经皮损内注射5-氟尿嘧啶治疗后消退。
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