英国老年成年人中加速度计评估的身体活动和久坐时间与身体功能的双向关联：EPIC-诺福克队列研究
Bidirectional associations of accelerometer-assessed physical activity and sedentary time with physical function among older English adults: the EPIC-Norfolk cohort study.
作者信息
Yerrakalva Dharani, Hajna Samantha, Wijndaele Katrien, Dempsey Paddy C, Westgate Kate, Wareham Nick, Griffin Simon J, Brage Soren
机构信息
Department of Public Health and Primary Care, University of Cambridge, School of Clinical Medicine, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge, CB2 0SR UK.
MRC Epidemiology Unit, University of Cambridge, School of Clinical Medicine, Cambridge, UK.
出版信息
Eur J Ageing. 2022 Oct 21;19(4):1507-1517. doi: 10.1007/s10433-022-00733-y. eCollection 2022 Dec.
UNLABELLED
To develop healthy ageing interventions, longitudinal associations between objectively assessed physical behaviours and physical function need to be better understood. We assessed associations between accelerometer-assessed total physical activity (PA), moderate-to-vigorous physical activity (MVPA), light physical activity (LPA), sedentary time and prolonged sedentary bout time, and clinically assessed physical function (grip strength, usual walking speed (UWS), chair stand speed) at two time-points in 3188 participants (≥ 60 years) of the EPIC-Norfolk study. Bidirectional associations were assessed using multivariable linear regression. Over an average of 6.1 years, baseline physical behaviours (greater total PA, MVPA and LPA, and less sedentary time) were associated with better subsequent walking and chair stand speed. Better baseline physical function was associated with better follow-up physical behaviours. There were no bidirectional associations between changes in physical behaviours and grip strength. Improvements in UWS were associated with improvements in all physical behaviours. Improvements in chair stand speed were associated with improvements in total PA, MVPA, and sedentary bout time. Improvements in physical behaviours were associated with improvements in UWS (3.1 cm/s/yr per 100 cpm/yr total PA, 3.6 cm/s/yr per hr/day/yr MVPA, 2.5 cm/s/yr per hr/day/yr LPA, - 2.9 cm/s/yr per hour/day/yr sedentary time, and - 1.6 cm/s/yr per hr/day/yr prolonged sedentary bout time). Only improvements in total PA, MVPA and sedentary bout time were associated with improvements in chair stand speed. In conclusion, we found bidirectional associations between changes in some physical behaviours and physical function and between baseline physical behaviours and subsequent physical function, highlighting the importance of considering the full range of physical behaviours to promote healthy ageing.
SUPPLEMENTARY INFORMATION
The online version contains supplementary material available at 10.1007/s10433-022-00733-y.
未标注
为了制定健康老龄化干预措施，需要更好地了解客观评估的身体行为与身体功能之间的纵向关联。我们在EPIC-诺福克研究的3188名参与者（≥60岁）的两个时间点评估了加速度计评估的总身体活动（PA）、中度至剧烈身体活动（MVPA）、轻度身体活动（LPA）、久坐时间和久坐时间延长与临床评估的身体功能（握力、通常步行速度（UWS）、从椅子上站起的速度）之间的关联。使用多变量线性回归评估双向关联。平均随访6.1年，基线身体行为（更高的总PA、MVPA和LPA，以及更少的久坐时间）与随后更好的步行和从椅子上站起的速度相关。更好的基线身体功能与更好的随访身体行为相关。身体行为变化与握力之间没有双向关联。UWS的改善与所有身体行为的改善相关。从椅子上站起速度的改善与总PA、MVPA和久坐时间延长的改善相关。身体行为的改善与UWS的改善相关（总PA每增加100次/分钟/年，UWS增加3.1厘米/秒/年；MVPA每增加1小时/天/年，UWS增加3.6厘米/秒/年；LPA每增加1小时/天/年，UWS增加2.5厘米/秒/年；久坐时间每增加1小时/天/年，UWS减少2.9厘米/秒/年；久坐时间延长每增加1小时/天/年，UWS减少1.6厘米/秒/年）。只有总PA、MVPA和久坐时间延长的改善与从椅子上站起速度的改善相关。总之，我们发现一些身体行为变化与身体功能之间以及基线身体行为与随后身体功能之间存在双向关联，突出了考虑全面身体行为对促进健康老龄化的重要性。
补充信息
在线版本包含可在10.1007/s10433-022-00733-y获取的补充材料。
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