目的：英国队列中的久坐时间、中度至剧烈身体活动及身体能力
Objective Sedentary Time, Moderate-to-Vigorous Physical Activity, and Physical Capability in a British Cohort.
作者信息
Keevil Victoria L, Cooper Andrew J M, Wijndaele Katrien, Luben Robert, Wareham Nicholas J, Brage Soren, Khaw Kay-Tee
机构信息
1Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge, Cambridge, UNITED KINGDOM; and 2MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Addenbrookes Biomedical Campus, Cambridge, UNITED KINGDOM.
出版信息
Med Sci Sports Exerc. 2016 Mar;48(3):421-9. doi: 10.1249/MSS.0000000000000785.
PURPOSE
Sedentariness has been proposed as an independent risk factor for poor health. However, few studies have considered associations of sedentary time (ST) with physical functional health independent of time spent in moderate-to-vigorous physical activity (MVPA).
METHODS
Community-based men and women (n = 8623, 48-92 yr old) in the European Prospective Investigation of Cancer-Norfolk study attended a health examination for objective measurement of physical capability, including grip strength (Smedley dynamometer (kg)), usual walking speed (UWS (cm·s(-1))), and timed chair stand speed (TCSS (stands per minute)). Of these, 4051 participants wore an accelerometer (GT1M ActiGraph) for 7 d to estimate time spent in MVPA (MVPA, ≥1952 counts per minute) and ST (ST, <100 counts per minute). Relations between physical capability outcomes and both MVPA and ST were explored using linear regression. The mutual independence of associations was also tested, and ST-MVPA interactions were explored using fractional polynomial models to account for nonlinear associations.
RESULTS
Men in the highest compared with those in the lowest sex-specific quartile of MVPA were stronger (1.84 kg; 95% confidence interval (CI), 0.79-2.89), had faster UWS (11.7 cm·s(-1); 95% CI, 8.4-15.1) and faster TCSS (2.35 stands per minute; 95% CI, 1.11-3.59) after multivariable adjustment. Similarly, women in the highest quartile of MVPA were stronger (2.47 kg; 95% CI, 1.79-3.14) and had faster UWS (15.5 cm·s(-1); 95% CI, 12.4-18.6) and faster TCSS (3.27 stands per minute; 95% CI, 2.19-4.25). Associations persisted after further adjustment for ST. Associations between higher ST and lower physical capability were also observed, but these were attenuated after accounting for MVPA. Furthermore, no MVPA-ST interactions were observed (Pinteractions > 0.05).
CONCLUSIONS
More time spent in MVPA was associated with higher physical capability, but there were no independent ST associations.
目的
久坐已被认为是健康状况不佳的一个独立风险因素。然而，很少有研究考虑久坐时间（ST）与身体功能健康之间的关联，而不考虑中度至剧烈身体活动（MVPA）所花费的时间。
方法
欧洲癌症前瞻性调查-诺福克研究中的社区男性和女性（n = 8623，年龄48 - 92岁）参加了健康检查，以客观测量身体能力，包括握力（斯梅德利测力计（kg））、通常步行速度（UWS（cm·s⁻¹））和定时从椅子上站起速度（TCSS（每分钟站起次数））。其中，4051名参与者佩戴加速度计（GT1M ActiGraph）7天，以估计MVPA（MVPA，≥1952次/分钟）和ST（ST，<100次/分钟）所花费的时间。使用线性回归探讨身体能力结果与MVPA和ST之间的关系。还测试了关联的相互独立性，并使用分数多项式模型探讨ST - MVPA相互作用，以考虑非线性关联。
结果
在多变量调整后，MVPA处于最高性别特异性四分位数的男性比处于最低四分位数的男性更强壮（1.84 kg；95%置信区间（CI），0.79 - 2.89），UWS更快（11.7 cm·s⁻¹；95% CI，8.4 - 15.1），TCSS更快（2.35次/分钟；95% CI，1.11 - 3.59）。同样，MVPA处于最高四分位数的女性更强壮（2.47 kg；95% CI，1.79 - 3.14），UWS更快（15.5 cm·s⁻¹；95% CI，12.4 - 18.6），TCSS更快（3.27次/分钟；95% CI，2.19 - 4.25）。在进一步调整ST后，关联仍然存在。还观察到较高的ST与较低的身体能力之间存在关联，但在考虑MVPA后这些关联减弱。此外，未观察到MVPA - ST相互作用（P相互作用>0.05）。
结论
花在MVPA上的时间越多与更高的身体能力相关，但不存在独立的ST关联。
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