Lee Way Seah, Arai Katsuhiro, Alex George, Treepongkaruna Suporn, Kim Kyung Mo, Choong Chee Liang, Mercado Karen Calixto, Darma Andy, Srivastava Anshu, Aw Marion M
Department of Paediatrics, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia.
Department of Population Medicine, Faculty of Medicine and Health Sciences, University Tunku Abdul Rahman, 59100, Kajang, Selangor, Malaysia.
J Gastroenterol Hepatol. 2023 Apr;38(4):510-522. doi: 10.1111/jgh.16084. Epub 2023 Jan 13.
Disease phenotype of pediatric inflammatory bowel disease (PIBD) in children from the Asia-Pacific region differs from that of children from the West. Many parts of Asia are endemic for tuberculosis, making diagnosis and management of pediatric Crohn's disease a challenge. Current available guidelines, mainly from Europe and North America, may not be completely applicable to clinicians caring for children with PIBD in Asia due to differences in disease characteristics and regional resource constraints. This position paper is an initiative from the Asian Pan-Pacific Society for Pediatric Gastroenterology, Hepatology and Nutrition (APPSPGHAN) that aims to provide an up-to-date, evidence-based approach to PIBD in the Asia-Pacific region. A group of pediatric gastroenterologists with a special interest in PIBD performed an extensive literature search covering epidemiology, disease characteristics and natural history, management, and monitoring. Attention was paid to publications from the region with special consideration to a resource-limited setting. This current position paper deals with surgical management, disease monitoring, immunization, bone health, and nutritional issues of PIBD in Asia. A special section on differentiating pediatric Crohn's disease from tuberculosis in children is included. This position paper provides a useful guide to clinicians in the surgical management, disease monitoring, and various health issues in children with IBD in Asia-Pacific region.
亚太地区儿童的小儿炎症性肠病(PIBD)的疾病表型与西方儿童不同。亚洲许多地区是结核病的流行地区,这使得小儿克罗恩病的诊断和管理成为一项挑战。由于疾病特征和区域资源限制的差异,目前主要来自欧洲和北美的现有指南可能并不完全适用于照顾亚太地区PIBD儿童的临床医生。本立场文件是亚洲太平洋小儿胃肠病学、肝病学和营养学会(APPSPGHAN)发起的一项倡议,旨在为亚太地区的PIBD提供一种最新的、基于证据的方法。一群对PIBD有特殊兴趣的小儿胃肠病学家进行了广泛的文献检索,涵盖流行病学、疾病特征和自然史、管理及监测。检索时特别关注了该地区的出版物,并特别考虑了资源有限的情况。本当前立场文件涉及亚洲PIBD的手术管理、疾病监测、免疫接种、骨骼健康和营养问题。其中还包括一个关于区分小儿克罗恩病和儿童结核病的特别章节。本立场文件为亚太地区IBD儿童的手术管理、疾病监测及各种健康问题的临床医生提供了有用的指导。