Breitling Vivian, Leha Andreas, Schiller Stina, Kruizenga Marie, Gärtner Jutta, Rosewich Hendrik
Division of Pediatric Neurology, Department of Pediatrics and Adolescent Medicine, University Medical Center Göttingen, Göttingen, Germany.
Department of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.
Pediatr Neurol. 2023 Feb;139:43-48. doi: 10.1016/j.pediatrneurol.2022.11.007. Epub 2022 Nov 14.
In the Division of Pediatric Neurology at the University Medical Center Göttingen we observed that many patients with Bell palsy are overweight or obese. To evaluate whether overweight and obesity are associated with increased risk of Bell palsy in children we conducted this single-centered retrospective study by performing a database search for International Classification of Diseases (ICD)-10 primary and secondary diagnosis of G51.0 (facial nerve palsy) between January 1, 2010, and December 31, 2020.
For risk assessment, patients' body mass indices (BMIs) were compared with BMI data of controls from a nationwide child health survey.
In total, 202 patients with peripheral facial nerve palsies (pFPs) were included, of which nearly half were classified as Bell palsies; 38% and 24% of the patients with Bell palsy and pFP had a BMI above the 90th percentile, respectively. High BMI was associated with statistically increased odds of Bell palsy in the group of overweight and obese patients (BMI >90th percentile; odds ratio [OR], 2.42; 95% confidence interval [CI], 1.6 to 3.8; P < 0.001) and solely obese patients (BMI >97th percentile; OR, 2.43; 95% CI, 1.4 to 4.3; P = 0.003).
We could confirm our observation that overweight and obesity are associated with increased risk of Bell palsy in children.
在哥廷根大学医学中心儿科神经科,我们观察到许多贝尔面瘫患者超重或肥胖。为了评估超重和肥胖是否与儿童贝尔面瘫风险增加相关,我们通过对2010年1月1日至2020年12月31日期间国际疾病分类(ICD)-10中G51.0(面神经麻痹)的原发性和继发性诊断进行数据库搜索,开展了这项单中心回顾性研究。
为了进行风险评估,将患者的体重指数(BMI)与一项全国儿童健康调查中对照组的BMI数据进行比较。
总共纳入了202例周围性面神经麻痹(pFP)患者,其中近一半被归类为贝尔面瘫;贝尔面瘫患者和pFP患者中分别有38%和24%的BMI高于第90百分位数。在超重和肥胖患者组(BMI>第90百分位数;优势比[OR],2.42;95%置信区间[CI],1.6至3.8;P<0.001)以及仅肥胖患者组(BMI>第97百分位数;OR,2.43;95%CI,1.4至4.3;P=0.003)中,高BMI与贝尔面瘫的统计学显著增加的几率相关。
我们可以证实我们的观察结果,即超重和肥胖与儿童贝尔面瘫风险增加相关。