耳硬化症患者的综合前庭评估：一项病例对照研究。
Comprehensive vestibular evaluation in patients with Otosclerosis: a case control study.
作者信息
Rajati Mohsen, Jafarzadeh Sadegh, Javadzadeh Raziyeh, Disfani Mahboobeh Feiz, Yousefi Razieh
机构信息
Sinus and Surgical Endoscopic Research Center, Department of Otorhinolaryngology, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Audiology, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
出版信息
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(4):582-587. doi: 10.1007/s12070-022-03147-5. Epub 2022 Nov 4.
AIM
Otosclerosis is one of the common otologic diseases. The mechanism and the probable site of vestibular involvement are not yet fully understood. The present study aimed to perform a comprehensive vestibular evaluation in patients with otosclerosis, compared to the cases without otosclerosis.
MATERIALS AND METHODS
patients underwent a comprehensive cochleovestibular evaluation, including audiometry, ocular and cervical vestibular evoked myogenic potential (o-VEMP and c-VEMP), video head impulse (vHIT) and caloric tests. The results were compared with those obtained from the non-otosclerosis control group.
RESULTS
A total of 61 individuals were included in the study who were divided into two groups of the case (50.82%) and control (49.18%). The results showed that there was a significant difference in the mean vHIT gain between the case and control groups (P < 0.05). However, the gain was still within the normal range. Besides, the patients with otosclerosis had significant bilateral or unilateral weaknesses according to caloric test results. Moreover, their o-VEMP and c-VEMP results were significantly abnormal as well (P < 0.05).
CONCLUSION
Based on the results of the present study, the vestibular system even in asymptomatic cases, is affected by otosclerosis. Furthermore, it seems that the otolithic system has a higher chance of involvement, compared to the semicircular canals.
SUPPLEMENTARY INFORMATION
The online version contains supplementary material available at 10.1007/s12070-022-03147-5.
目的
耳硬化症是常见的耳科疾病之一。其前庭受累的机制和可能部位尚未完全明确。本研究旨在对耳硬化症患者进行全面的前庭评估，并与非耳硬化症患者进行比较。
材料与方法
患者接受了全面的耳蜗前庭评估，包括听力测定、眼和颈前庭诱发肌源性电位（o-VEMP和c-VEMP）、视频头脉冲试验（vHIT）和冷热试验。将结果与非耳硬化症对照组获得的结果进行比较。
结果
本研究共纳入61例个体，分为病例组（50.82%）和对照组（49.18%）。结果显示，病例组和对照组之间的平均vHIT增益存在显著差异（P < 0.05）。然而，该增益仍在正常范围内。此外，根据冷热试验结果，耳硬化症患者存在显著的双侧或单侧功能减弱。而且，他们的o-VEMP和c-VEMP结果也显著异常（P < 0.05）。
结论
根据本研究结果，即使是无症状的耳硬化症患者，其前庭系统也会受到影响。此外，与半规管相比，耳石系统似乎更易受累。
补充信息
在线版本包含可在10.1007/s12070-022-03147-5获取的补充材料。
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