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阿哌沙班与依替巴肽在透析伴房颤患者中的应用:P2Y12 抑制剂抗凝方案对预后的影响。

Apixaban versus No Anticoagulation by P2Y12 Inhibitor Prescription Status in Dialysis Patients with Atrial Fibrillation.

机构信息

Division of Nephrology, Department of Medicine, McGill University Health Center, Montreal, Quebec, Canada.

Nephrology Division, Department of Medicine, New York University Langone Medical Center, New York, New York.

出版信息

Kidney360. 2022 Aug 1;3(10):1769-1771. doi: 10.34067/KID.0003002022. eCollection 2022 Oct 27.

Abstract

In patients with atrial fibrillation on dialysis, the incidence of stroke was similar with apixaban or no anticoagulation, regardless of P2Y12 prescription.In patients with atrial fibrillation on dialysis who were on a P2Y12 inhibitor, apixaban increased the risk of bleeding, compared with no anticoagulation.The incidence of myocardial infarction or ischemic stroke was similar with apixaban or no anticoagulation, regardless of P2Y12 prescription status.

摘要

在接受透析治疗的房颤患者中,无论是否开具了 P2Y12 处方,阿哌沙班或不抗凝治疗的卒中发生率相似。在接受透析治疗且正在服用 P2Y12 抑制剂的房颤患者中,与不抗凝治疗相比,阿哌沙班增加了出血风险。无论 P2Y12 处方状态如何,阿哌沙班或不抗凝治疗的心肌梗死或缺血性卒中发生率相似。

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