硬皮病：致病因素与当前治疗方法

Aust N Z J Med. 1978;8 Suppl 1:143-8. doi: 10.1111/j.1445-5994.1978.tb04809.x.

The aetiology of scleroderma remains unknown. Pathogenetic mechanisms may originate from vascular, collagen or immune abnormalities. These are reviewed and the current management although in the main unsatisfactory may alleviate a number of the distressing symptoms.

硬皮病的病因尚不清楚。发病机制可能源于血管、胶原蛋白或免疫异常。本文对这些方面进行了综述，目前的治疗方法虽然总体上不尽人意，但可能会缓解一些令人痛苦的症状。