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[犬利什曼病:关于诊断、治疗方法及监测的最新进展]

[Canine leishmaniosis: an update regarding diagnostics, therapeutic approaches, and monitoring].

作者信息

Schäfer Ingo, Müller Elisabeth, Naucke Torsten J

机构信息

LABOKLIN GmbH and Co. KG.

出版信息

Tierarztl Prax Ausg K Kleintiere Heimtiere. 2022 Dec;50(6):431-445. doi: 10.1055/a-1970-9590. Epub 2022 Dec 14.

Abstract

Canine infections with () are gaining significance in Germany due to rising numbers of dogs imported from endemic countries, frequent travel and changing of climatic conditions in Central Europe. Dogs without any clinical signs suspicious for vector-borne infections imported from other countries to Germany should be tested immediately after import and 6 months later. In dogs with clinical signs suspicious for leishmaniosis, direct and indirect detection methods of the pathogen as well as hematology, biochemistry, serum protein electrophoresis and C-reactive protein are recommended. For treatment and monitoring of canine leishmaniosis, the LeishVet-guidelines are highly recommended. Different therapeutic options include , , and drugs. For dose adjustments of allopurinol, the "step plan" should be taken in consideration. Due to climatic changes, habitats of sandflies as transmitting vectors of leishmaniosis are expanding. Next to vectorial transmission mating, transplacental infections, bite wounds, and blood transfusions were described in canine leishmaniosis. Additionally, is a zoonotic vector-borne infectious pathogen, which is important regarding the "One-health"-aspect.

摘要

由于从流行国家进口的犬只数量增加、频繁旅行以及中欧气候条件的变化,德国犬类感染()的情况日益严重。从其他国家进口到德国且无任何疑似媒介传播感染临床症状的犬只,应在进口后立即进行检测,并在6个月后再次检测。对于有疑似利什曼病临床症状的犬只,建议采用病原体的直接和间接检测方法以及血液学、生物化学、血清蛋白电泳和C反应蛋白检测。对于犬利什曼病的治疗和监测,强烈推荐遵循LeishVet指南。不同的治疗选择包括、和药物。对于别嘌呤醇的剂量调整,应考虑“逐步计划”。由于气候变化,作为利什曼病传播媒介的白蛉栖息地正在扩大。除了媒介传播交配外,犬利什曼病还存在经胎盘感染、咬伤和输血感染的情况。此外,(病原体名称缺失)是一种人畜共患的媒介传播感染病原体,在“同一健康”方面具有重要意义。

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