• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新型苯并呋喃 - 咪唑类抗真菌剂。I. 合成与表征

New benzofuran-imidazoles as antimycotic agents. I. Synthesis and characterization.

作者信息

Pestellini V, Giannotti D, Giolitti A, Fantò N, Riviera L, Bellotti M G

机构信息

Menarini Farmaceutici, Dept. of Chemistry, Firenze, Italy.

出版信息

Chemioterapia. 1987 Aug;6(4):269-71.

PMID:3652277
Abstract

With the aim of obtaining new drugs having antimycotic activity together with antibacterial and fewer side effects, we synthesized ten new benzofuran-2-yl-imidazoles.

摘要

为了获得具有抗真菌活性以及抗菌活性且副作用较少的新药,我们合成了十种新型苯并呋喃 -2-基 -咪唑。

相似文献

1
New benzofuran-imidazoles as antimycotic agents. I. Synthesis and characterization.新型苯并呋喃 - 咪唑类抗真菌剂。I. 合成与表征
Chemioterapia. 1987 Aug;6(4):269-71.
2
Synthesis and antimicrobial activity of some novel derivatives of benzofuran: part 2. The synthesis and antimicrobial activity of some novel 1-(1-benzofuran-2-yl)-2-mesitylethanone derivatives.苯并呋喃的一些新型衍生物的合成与抗菌活性:第2部分。一些新型1-(1-苯并呋喃-2-基)-2-均三甲苯基乙酮衍生物的合成与抗菌活性。
Eur J Med Chem. 2008 Feb;43(2):300-8. doi: 10.1016/j.ejmech.2007.03.023. Epub 2007 Apr 7.
3
Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes.某些芳基[3-(咪唑-1-基/三唑-1-基甲基)苯并呋喃-2-基]酮肟的合成及其抗真菌活性
Eur J Med Chem. 2006 May;41(5):651-6. doi: 10.1016/j.ejmech.2005.12.013. Epub 2006 Mar 22.
4
Antifungal agents. 10. Synthesis and antifungal activities of aryl-(1H-imidazol-1-yl)-(isoquinolin-1-yl) methane derivatives.抗真菌剂。10. 芳基-(1H-咪唑-1-基)-(异喹啉-1-基)甲烷衍生物的合成与抗真菌活性
Farmaco. 1995 Apr;50(4):227-38.
5
Synthesis and antimicrobial evaluation of 1-(benzofuran-2-yl)-4-nitro-3-arylbutan-1-ones and 3-(benzofuran-2-yl)-4,5-dihydro-5-aryl-1-[4-(aryl)-1,3-thiazol-2-yl]-1H-pyrazoles.1-(苯并呋喃-2-基)-4-硝基-3-芳基丁-1-酮和3-(苯并呋喃-2-基)-4,5-二氢-5-芳基-1-[4-(芳基)-1,3-噻唑-2-基]-1H-吡唑的合成与抗菌活性评价
Eur J Med Chem. 2009 Jun;44(6):2632-5. doi: 10.1016/j.ejmech.2008.09.029. Epub 2008 Oct 2.
6
[Substances with antibacterial and antifungal activity. I. Synthesis and microbiologic activity of imidazolylmethylanilines].
Farmaco Sci. 1986 Apr;41(4):292-307.
7
[Antibacterial and antifungal agents. IV. Synthesis and antifungal activity of econazole analogs with pyrrole structure].
Farmaco Sci. 1985 May;40(5):315-24.
8
Synthesis and antibacterial activity of egonol derivatives.丁香酚衍生物的合成及其抗菌活性
Bioorg Med Chem. 2008 Apr 15;16(8):4431-7. doi: 10.1016/j.bmc.2008.02.057. Epub 2008 Mar 5.
9
Synthesis of 1-{4-[4-(adamant-1-yl)phenoxymethyl]-2-(4-bromophenyl)- 1,3-dioxolan-2-ylmethyl}imidazole with expected antifungal and antibacterial activity.具有预期抗真菌和抗菌活性的1-{4-[4-(金刚烷-1-基)苯氧基甲基]-2-(4-溴苯基)-1,3-二氧戊环-2-基甲基}咪唑的合成
Acta Pol Pharm. 2007 Nov-Dec;64(6):535-41.
10
Antifungal agents. 11. N-substituted derivatives of 1-[(aryl)(4-aryl-1H-pyrrol-3-yl)methyl]-1H-imidazole: synthesis, anti-Candida activity, and QSAR studies.抗真菌剂。11. 1-[(芳基)(4-芳基-1H-吡咯-3-基)甲基]-1H-咪唑的N-取代衍生物:合成、抗念珠菌活性及定量构效关系研究
J Med Chem. 2005 Aug 11;48(16):5140-53. doi: 10.1021/jm048997u.

引用本文的文献

1
Multicomponent synthesis of chromophores - The one-pot approach to functional π-systems.发色团的多组分合成——功能性π体系的一锅法
Front Chem. 2023 Mar 17;11:1124209. doi: 10.3389/fchem.2023.1124209. eCollection 2023.
2
Studies on the binding of nitrogenous bases to protoporphyrin IX iron(II) in aqueous solution at high pH values.在高 pH 值的水溶液中研究含氮碱基与原卟啉 IX 铁(II)的结合。
J Biol Inorg Chem. 2022 Apr;27(3):297-313. doi: 10.1007/s00775-022-01929-4. Epub 2022 Mar 2.
3
Practical catalytic asymmetric synthesis of diaryl-, aryl heteroaryl-, and diheteroarylmethanols.
二芳基甲醇、芳基杂芳基甲醇和二杂芳基甲醇的实用催化不对称合成。
J Am Chem Soc. 2009 Sep 2;131(34):12483-93. doi: 10.1021/ja9046747.