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本文引用的文献

1
Expert Panel Guidance and Narrative Review of Treatment Simplification of Complex Insulin Regimens to Improve Outcomes in Type 2 Diabetes.专家小组关于简化复杂胰岛素治疗方案以改善2型糖尿病治疗效果的指南及叙述性综述
Diabetes Ther. 2022 Apr;13(4):619-634. doi: 10.1007/s13300-022-01222-2. Epub 2022 Mar 11.
2
13. Older Adults: Standards of Medical Care in Diabetes-2022.13. 老年人：2022 年糖尿病医学护理标准。
Diabetes Care. 2022 Jan 1;45(Suppl 1):S195-S207. doi: 10.2337/dc22-S013.
3
Veterans' Interpretation of Diabetes Distress in Diabetes Self-Management: Findings From Cognitive Interviews.退伍军人对糖尿病自我管理中糖尿病困扰的解读：认知访谈研究结果。
Sci Diabetes Self Manag Care. 2021 Oct;47(5):391-403. doi: 10.1177/26350106211043487. Epub 2021 Sep 24.
4
Simplification of complex insulin therapy: a story of dogma and therapeutic resignation.简化复杂的胰岛素治疗：教条与治疗妥协的故事。
Diabetes Res Clin Pract. 2021 Aug;178:108958. doi: 10.1016/j.diabres.2021.108958. Epub 2021 Jul 16.
5
Applied Rapid Qualitative Analysis to Develop a Contextually Appropriate Intervention and Increase the Likelihood of Uptake.应用快速定性分析来制定一个具有文化适应性的干预措施，从而提高采用的可能性。
Med Care. 2021 Jun 1;59(Suppl 3):S242-S251. doi: 10.1097/MLR.0000000000001553.
6
Clinical factors associated with persistently poor diabetes control in the Veterans Health Administration: A nationwide cohort study.与退伍军人健康管理局中持续较差的糖尿病控制相关的临床因素：一项全国性队列研究。
PLoS One. 2019 Mar 29;14(3):e0214679. doi: 10.1371/journal.pone.0214679. eCollection 2019.
7
Simplification of Insulin Regimen in Older Adults and Risk of Hypoglycemia.老年患者胰岛素治疗方案简化与低血糖风险
JAMA Intern Med. 2016 Jul 1;176(7):1023-5. doi: 10.1001/jamainternmed.2016.2288.
8
Initial validation of a self-report measure of the extent of and reasons for medication nonadherence.初步验证了一种自我报告的药物不依从程度及其原因的测量方法。
Med Care. 2012 Dec;50(12):1013-9. doi: 10.1097/MLR.0b013e318269e121.
9
Patient adherence to medication requirements for therapy of type 2 diabetes.患者对 2 型糖尿病治疗药物要求的依从性。
Int J Clin Pract. 2011 Mar;65(3):314-22. doi: 10.1111/j.1742-1241.2010.02544.x.
10
Regional, Geographic, and Ethnic Differences in Medication Adherence Among Adults with Type 2 Diabetes.2型糖尿病成年患者用药依从性的地区、地理和种族差异
Ann Pharmacother. 2011 Feb;45(2):169-78. doi: 10.1345/aph.1P442.

简化治疗以确保血糖控制和参与（STAGE）在控制不佳的糖尿病：一项试点研究。

Simplifying therapy to assure glycemic control and engagement (STAGE) in poorly-controlled diabetes: A pilot study.

机构信息

Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA Medical Center, Durham, NC 27710, United States; Department of Medicine, Division of Endocrinology, Duke University Medical Center, Rd, Durham, NC 27710, United States.

Department of Medicine, Division of Endocrinology, Duke University Medical Center, Rd, Durham, NC 27710, United States.

出版信息

J Diabetes Complications. 2023 Jan;37(1):108364. doi: 10.1016/j.jdiacomp.2022.108364. Epub 2022 Dec 5.

DOI:10.1016/j.jdiacomp.2022.108364
PMID:36525906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9839589/
Abstract

In this single-arm pilot study, we demonstrated feasibility and acceptability of an insulin simplification intervention in patients with persistent, poorly-controlled type 2 diabetes on complex insulin regimens. While not powered to assess clinical outcomes, we observed neither worsened glycemic control nor increased hypoglycemia.

摘要

在这项单臂先导研究中，我们证明了在持续、血糖控制不佳的 2 型糖尿病患者中，实施复杂胰岛素方案简化干预的可行性和可接受性。虽然没有足够的效能评估临床结局，但我们既未观察到血糖控制恶化，也未观察到低血糖增加。