人类载脂蛋白B基因的DNA序列。
DNA sequence of the human apolipoprotein B gene.
作者信息
Ludwig E H, Blackhart B D, Pierotti V R, Caiati L, Fortier C, Knott T, Scott J, Mahley R W, Levy-Wilson B, McCarthy B J
机构信息
Gladstone Foundation Laboratories, Cardiovascular Research Institute, San Francisco, CA 94140.
出版信息
DNA. 1987 Aug;6(4):363-72. doi: 10.1089/dna.1987.6.363.
The sequence of the human apolipoprotein B gene comprises 43 kb divided into 29 exons, one of which is unusually long and contains 7572 bp. Comparison of the gene sequence with four complete and three partial cDNA sequences published elsewhere reveals a total of 60 nucleotide substitutions and 39 amino acid substitutions and one small deletion in the signal peptide.
人类载脂蛋白B基因序列由43kb组成，分为29个外显子，其中一个外显子异常长，包含7572bp。将该基因序列与其他地方发表的四个完整和三个部分cDNA序列进行比较，结果显示共有60个核苷酸替换、39个氨基酸替换以及信号肽中的一个小缺失。
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