• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Multiple primary lung cancer tumors with diversified genetic mutations-complications in choosing therapeutic options.具有多种基因突变的多原发性肺癌肿瘤——治疗方案选择中的复杂性
Clin Transl Discov. 2022 Sep;2(3). doi: 10.1002/ctd2.123. Epub 2022 Aug 3.
2
The Common Thread: A Case of Synchronous Lung Cancers and a Germline CHEK2 Mutation.共同线索：一例同步肺癌和种系 CHEK2 突变。
Clin Lung Cancer. 2022 Jan;23(1):e1-e4. doi: 10.1016/j.cllc.2021.05.011. Epub 2021 Jun 12.
3
Proposal for a Combined Histomolecular Algorithm to Distinguish Multiple Primary Adenocarcinomas from Intrapulmonary Metastasis in Patients with Multiple Lung Tumors.多原发肺腺癌与多发性肺肿瘤患者肺内转移的组织分子联合算法鉴别诊断的建议。
J Thorac Oncol. 2019 May;14(5):844-856. doi: 10.1016/j.jtho.2019.01.017. Epub 2019 Feb 2.
4
The High Proportion of Discordant Mutations among Multiple Lung Tumors.多个肺肿瘤中不一致突变的高比例。
Cancers (Basel). 2022 Jun 18;14(12):3011. doi: 10.3390/cancers14123011.
5
Favorable prognosis and high discrepancy of genetic features in surgical patients with multiple primary lung cancers.手术治疗多原发性肺癌患者具有良好的预后和高度的遗传特征差异。
J Thorac Cardiovasc Surg. 2018 Jan;155(1):371-379.e1. doi: 10.1016/j.jtcvs.2017.08.141. Epub 2017 Oct 5.
6
Exploring the spatiotemporal genetic heterogeneity in metastatic lung adenocarcinoma using a nuclei flow-sorting approach.利用核流分选方法探索转移性肺腺癌的时空遗传异质性。
J Pathol. 2019 Feb;247(2):199-213. doi: 10.1002/path.5183. Epub 2018 Dec 28.
7
Comprehensive Mutation Profiling of Colorectal Cancer Patients With Lung or Liver Metastasis by Targeted Next-Generation Sequencing.通过靶向下一代测序对肺或肝转移的结直肠癌患者进行全面的基因突变分析。
Technol Cancer Res Treat. 2023 Jan-Dec;22:15330338231185285. doi: 10.1177/15330338231185285.
8
KRAS mutations in primary colorectal cancer tumors and related metastases: a potential role in prediction of lung metastasis.结直肠癌原发肿瘤及其相关转移灶中的 KRAS 突变：在预测肺转移中的潜在作用。
PLoS One. 2009 Dec 18;4(12):e8199. doi: 10.1371/journal.pone.0008199.
9
Discordance of epidermal growth factor receptor mutations between primary tumors and corresponding mediastinal nodal metastases in patients operated on for stage N2 non-small cell lung cancer.N2期非小细胞肺癌手术患者中原发肿瘤与相应纵隔淋巴结转移灶之间表皮生长因子受体突变的不一致性。
Thorac Cancer. 2012 Nov;3(4):313-319. doi: 10.1111/j.1759-7714.2012.00163.x.
10
Clinical and Genomic Features of Exon 20 Insertion Mutations and Characterization of Expression by Immunohistochemistry in East Asian Non-Small-Cell Lung Cancer.东亚非小细胞肺癌中外显子 20 插入突变的临床和基因组特征及免疫组织化学表达特征。
JCO Precis Oncol. 2022 Oct;6:e2200278. doi: 10.1200/PO.22.00278.

本文引用的文献

1
Clinical implications of EGFR-associated MAPK/ERK pathway in multiple primary lung cancer.表皮生长因子受体（EGFR）相关的丝裂原活化蛋白激酶/细胞外信号调节激酶（MAPK/ERK）通路在多原发性肺癌中的临床意义
Clin Transl Med. 2022 May;12(5):e847. doi: 10.1002/ctm2.847.
2
Recent Advances in the Diagnosis and Management of Multiple Primary Lung Cancer.多原发性肺癌诊断与治疗的最新进展
Cancers (Basel). 2022 Jan 4;14(1):242. doi: 10.3390/cancers14010242.
3
Genetic and immune characteristics of multiple primary lung cancers and lung metastases.多原发肺癌与肺转移瘤的遗传和免疫特征。
Thorac Cancer. 2021 Oct;12(19):2544-2550. doi: 10.1111/1759-7714.14134. Epub 2021 Sep 12.
4
Targeted Treatment of Multiple Primary Lung Cancers Harboring Distinct EGFR or RET Alterations: A Case Report.针对携带不同表皮生长因子受体（EGFR）或转染重排（RET）改变的多原发性肺癌的靶向治疗：一例报告
Clin Lung Cancer. 2021 Sep;22(5):e673-e677. doi: 10.1016/j.cllc.2020.12.005. Epub 2020 Dec 19.
5
Characteristics and prognosis of synchronous multiple primary lung cancer after surgical treatment: A systematic review and meta-analysis of current evidence.手术治疗后同步多原发性肺癌的特征和预后：当前证据的系统回顾和荟萃分析。
Cancer Med. 2021 Jan;10(2):507-520. doi: 10.1002/cam4.3614. Epub 2020 Dec 10.
6
Multiple Primary Lung Cancers: A New Challenge in the Era of Precision Medicine.多原发性肺癌：精准医学时代的新挑战
Cancer Manag Res. 2020 Oct 20;12:10361-10374. doi: 10.2147/CMAR.S268081. eCollection 2020.
7
Osimertinib in Resected -Mutated Non-Small-Cell Lung Cancer.奥希替尼治疗可切除突变型非小细胞肺癌。
N Engl J Med. 2020 Oct 29;383(18):1711-1723. doi: 10.1056/NEJMoa2027071. Epub 2020 Sep 19.
8
Genomic profiles and transcriptomic microenvironments in 2 patients with synchronous lung adenocarcinoma and lung squamous cell carcinoma: a case report.2例同步性肺腺癌和肺鳞癌患者的基因组图谱和转录组微环境：病例报告
BMC Med Genomics. 2020 Jan 31;13(1):15. doi: 10.1186/s12920-020-0663-8.
9
MAPK pathway activity plays a key role in PD-L1 expression of lung adenocarcinoma cells.MAPK 通路活性在肺腺癌细胞 PD-L1 表达中发挥关键作用。
J Pathol. 2019 Sep;249(1):52-64. doi: 10.1002/path.5280. Epub 2019 May 21.
10
Proposal for a Combined Histomolecular Algorithm to Distinguish Multiple Primary Adenocarcinomas from Intrapulmonary Metastasis in Patients with Multiple Lung Tumors.多原发肺腺癌与多发性肺肿瘤患者肺内转移的组织分子联合算法鉴别诊断的建议。
J Thorac Oncol. 2019 May;14(5):844-856. doi: 10.1016/j.jtho.2019.01.017. Epub 2019 Feb 2.

Multiple primary lung cancer tumors with diversified genetic mutations-complications in choosing therapeutic options.

作者信息

Comeau Jill, Beedupalli Kavitha, Jois Seetharama

机构信息

School of Clinical Sciences, College of Pharmacy, University of Louisiana Monroe, Shreveport, LA 71101.

School of Medicine, Louisiana State University Health Shreveport, Shreveport, LA 71103.

出版信息

Clin Transl Discov. 2022 Sep;2(3). doi: 10.1002/ctd2.123. Epub 2022 Aug 3.

DOI:10.1002/ctd2.123
PMID:36532867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9757724/
Abstract
摘要