Moradi Yaser, Jafarizadeh Hossein, Asghari Rahim, Mirzamohammadi Omid, Alinejad Vahid
Patient Safety Research Center, Clinical Research Institute, School of Nursing and Midwifery, Urmia University of Medical Sciences, Urmia, Iran.
Department of Oncology, Imam Khomeini hospital, Urmia University of Medical Sciences, Urmia, Iran.
Explore (NY). 2023 Jul-Aug;19(4):587-593. doi: 10.1016/j.explore.2022.11.006. Epub 2022 Nov 30.
Nausea and vomiting are the most common complications of chemotherapy encountered by cancer patients. To alleviate these complications and reduce patients' problems, it is necessary to use complementary methods.
The present study aimed to investigate the effect of single and combined use of the Benson relaxation technique and oxygen therapy on chemotherapy-induced nausea, vomiting, and retching in patients with gastric cancer.
This is a single-blind, four-arm, 2 × 2 factorial-design randomized clinical trial, in which a total of 100 patients with gastric cancer were enrolled and assigned to four groups of relaxation therapy, oxygen therapy, combined therapy, and control (n = 25 in each group) using simple random allocation. The intervention program included the application of Benson relaxation technique, supplemental oxygen therapy, and a combination of both. The control group merely received routine care. Data were collected using the Rhodes Index of Nausea and Vomiting Form 2 (INV-2).
The results of the Kruskal-Wallis H test showed that there was a statistically significant difference in the mean scores of nausea, vomiting, retching, and acute phase between the four groups (p = 0.001). However, there was a statistically significant difference only in the mean score of retching in this regard for the delayed phase (p = 0.02).
Overall, the single use of Benson relaxation technique and the combined use of this technique and oxygen therapy were shown to be more effective in managing chemotherapy-induced nausea and vomiting.
恶心和呕吐是癌症患者化疗最常见的并发症。为缓解这些并发症并减少患者的问题,有必要采用辅助方法。
本研究旨在探讨单独及联合使用本森放松技术和氧疗对胃癌患者化疗引起的恶心、呕吐和干呕的影响。
这是一项单盲、四臂、2×2析因设计的随机临床试验,共纳入100例胃癌患者,采用简单随机分配法将其分为放松治疗组、氧疗组、联合治疗组和对照组(每组n = 25)。干预方案包括应用本森放松技术、补充氧疗以及两者结合。对照组仅接受常规护理。使用罗兹恶心呕吐量表2(INV-2)收集数据。
Kruskal-Wallis H检验结果显示,四组之间恶心、呕吐、干呕和急性期的平均得分存在统计学显著差异(p = 0.001)。然而,在这方面,仅延迟期干呕的平均得分存在统计学显著差异(p = 0.02)。
总体而言,单独使用本森放松技术以及该技术与氧疗联合使用在管理化疗引起的恶心和呕吐方面更有效。