Department of Oncology, People's Hospital of Jiulongpo District, Chongqing, China.
Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Medicine (Baltimore). 2024 May 31;103(22):e38357. doi: 10.1097/MD.0000000000038357.
The objective of this study was to establish a nausea-free ward model and evaluate the effect of an intervention procedure guided by this model on chemotherapy-induced nausea and vomiting (CINV) in cancer patients. A total of 105 chemotherapy patients from March to September 2022 before the establishment of nausea-free ward in the Chongqing Jiulongpo District People's Hospital were selected as the control group as well as 105 chemotherapy patients from March to September 2023 after the establishment of nausea-free ward as the intervention group. The intervention group was managed by comprehensive standardized CINV management on the basis of the control group. Finally, the Chinese Society of Clinical Oncology grading tool for nausea and vomiting and the Functional Living Index-Emesis were used to evaluate the effect. Under the intervention of the nausea-free ward model, the intervention group exhibited significantly lower ratings of nausea and vomiting compared to the control group (all P-value <.05). The nausea score, vomiting score, and total score of the intervention group were significantly lower than the control group (all P-value <.05). Our study found CINV symptoms and quality of life can be significantly improved by the application of the nausea-free ward model. The nausea-free ward model is instructive in clinical practice and can guide clinical work as well as bring management experience to clinical workers.
本研究旨在建立一个无恶心病房模式,并评估该模式指导下的干预程序对癌症患者化疗引起的恶心和呕吐(CINV)的效果。2022 年 3 月至 9 月,在重庆市九龙坡区人民医院建立无恶心病房之前,选择了 105 名化疗患者作为对照组,2023 年 3 月至 9 月,在建立无恶心病房后,选择了 105 名化疗患者作为干预组。在对照组的基础上,干预组通过综合标准化的 CINV 管理进行管理。最后,使用中国临床肿瘤学会(CSCO)恶心和呕吐分级工具和生活功能指数-呕吐(FLIE)来评估效果。在无恶心病房模式的干预下,与对照组相比,干预组的恶心和呕吐评分明显降低(均 P 值<.05)。干预组的恶心评分、呕吐评分和总分均明显低于对照组(均 P 值<.05)。我们的研究发现,应用无恶心病房模式可以显著改善 CINV 症状和生活质量。无恶心病房模式在临床实践中有指导意义,可以指导临床工作,并为临床工作者带来管理经验。