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ISPAD Clinical Practice Consensus Guidelines 2022: Assessment and management of hypoglycemia in children and adolescents with diabetes.

作者信息

Abraham Mary B, Karges Beate, Dovc Klemen, Naranjo Diana, Arbelaez Ana Maria, Mbogo Joyce, Javelikar Ganesh, Jones Timothy W, Mahmud Farid H

机构信息

Department of Endocrinology and Diabetes, Perth Children's Hospital, Perth, Australia.

Children's Diabetes Centre, Telethon Kids Institute, The University of Western Australia, Perth, Australia.

出版信息

Pediatr Diabetes. 2022 Dec;23(8):1322-1340. doi: 10.1111/pedi.13443.

DOI:10.1111/pedi.13443
PMID:36537534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10107518/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be3/10107518/a0e7a3b8c97a/PEDI-23-1322-g031.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be3/10107518/a0e7a3b8c97a/PEDI-23-1322-g031.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be3/10107518/a0e7a3b8c97a/PEDI-23-1322-g031.jpg

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Dasiglucagon-A Next-Generation Glucagon Analog for Rapid and Effective Treatment of Severe Hypoglycemia: Results of Phase 3 Randomized Double-Blind Clinical Trial.Dasiglucagon-A 是一种新一代胰高血糖素类似物，可快速有效治疗严重低血糖：3 期随机双盲临床试验结果。
Diabetes Care. 2021 Jun 1;44(6):1361-1367. doi: 10.2337/dc20-2995.
2
Comparison of a ready-to-use liquid glucagon injection administered by autoinjector to glucagon emergency kit for the symptomatic relief of severe hypoglycemia: two randomized crossover non-inferiority studies.两种随机交叉非劣效性研究比较了自动注射器给予即用型液体胰高血糖素注射与胰高血糖素急救包在缓解严重低血糖症状方面的效果。
BMJ Open Diabetes Res Care. 2021 Oct;9(1). doi: 10.1136/bmjdrc-2021-002137.
3
Safety and Effectiveness of Oral Glyburide Suspension in Neonatal Diabetes Mellitus: French Retrospective Cohort Study.
口服格列本脲混悬液治疗新生儿糖尿病的安全性和有效性：法国回顾性队列研究
J Endocr Soc. 2025 May 9;9(7):bvaf083. doi: 10.1210/jendso/bvaf083. eCollection 2025 Jul.
4
Evaluation of the Effects of Incorporating Long-Acting Subcutaneous Insulin Into the Standard Treatment Protocol for Diabetic Ketoacidosis in Children.评估长效皮下注射胰岛素纳入儿童糖尿病酮症酸中毒标准治疗方案的效果。
Int J Endocrinol Metab. 2024 Mar 11;22(1):e139684. doi: 10.5812/ijem-139684. eCollection 2024 Jan.
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Improving Postoperative Pediatric Recovery by Efficient Recovery Room Care-A Comprehensive Review.通过高效的恢复室护理改善小儿术后恢复——一项综述
Children (Basel). 2025 Apr 28;12(5):568. doi: 10.3390/children12050568.
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Pediatr Diabetes. 2023 Oct 27;2023:7467652. doi: 10.1155/2023/7467652. eCollection 2023.
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The relationship between food addiction, eating attitudes, and psychiatric symptoms with metabolic control in adolescents with Type 1 Diabetes Mellitus.1型糖尿病青少年中食物成瘾、饮食态度及精神症状与代谢控制之间的关系。
J Eat Disord. 2025 Apr 2;13(1):58. doi: 10.1186/s40337-025-01242-w.
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Catechol-based chemistry for hypoglycemia-responsive delivery of zinc-glucagon via hydrogel-based microneedle patch technology.基于儿茶酚化学的低血糖响应性锌-胰高血糖素递送，通过水凝胶基微针贴片技术实现。
Nat Commun. 2025 Apr 1;16(1):3124. doi: 10.1038/s41467-025-58278-4.
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Performance of real-time continuous glucose monitoring during track and field training in adolescents with type 1 diabetes.1型糖尿病青少年田径训练期间实时连续血糖监测的表现
Pediatr Endocrinol Diabetes Metab. 2024;30(4):211-220. doi: 10.5114/pedm.2024.146685.
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Mini-Dose Glucagon for Mild and Moderate Hypoglycemia in Type 1 Diabetes.小剂量胰高血糖素用于1型糖尿病的轻中度低血糖症
Med Res Arch. 2024 Oct 29;12(10). doi: 10.18103/mra.v12i10.5866.
Comparing real-time and intermittently scanned continuous glucose monitoring in adults with type 1 diabetes (ALERTT1): a 6-month, prospective, multicentre, randomised controlled trial.
比较实时和间歇性扫描连续血糖监测在 1 型糖尿病成人患者中的应用（ALERTT1）：一项 6 个月前瞻性多中心随机对照试验。
Lancet. 2021 Jun 12;397(10291):2275-2283. doi: 10.1016/S0140-6736(21)00789-3. Epub 2021 Jun 2.
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Cognitive performance declines in older adults with type 1 diabetes: results from 32 years of follow-up in the DCCT and EDIC Study.1 型糖尿病老年患者认知功能下降：来自 DCCT 和 EDIC 研究 32 年随访的结果。
Lancet Diabetes Endocrinol. 2021 Jul;9(7):436-445. doi: 10.1016/S2213-8587(21)00086-3. Epub 2021 May 27.
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Dasiglucagon, a next-generation ready-to-use glucagon analog, for treatment of severe hypoglycemia in children and adolescents with type 1 diabetes: Results of a phase 3, randomized controlled trial.达格列净，一种新一代即用型胰高血糖素类似物，用于治疗 1 型糖尿病儿童和青少年的严重低血糖：3 期随机对照试验结果。
Pediatr Diabetes. 2021 Aug;22(5):734-741. doi: 10.1111/pedi.13220. Epub 2021 Jun 9.
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Glycemic Outcome Associated With Insulin Pump and Glucose Sensor Use in Children and Adolescents With Type 1 Diabetes. Data From the International Pediatric Registry SWEET.血糖控制结果与 1 型糖尿病患儿和青少年使用胰岛素泵和血糖传感器相关。来自国际儿科登记研究 SWEET 的数据。
Diabetes Care. 2021 May;44(5):1176-1184. doi: 10.2337/dc20-1674. Epub 2021 Mar 2.
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Impact of Type 1 Diabetes in the Developing Brain in Children: A Longitudinal Study.儿童发育期 1 型糖尿病对大脑的影响：一项纵向研究。
Diabetes Care. 2021 Apr;44(4):983-992. doi: 10.2337/dc20-2125. Epub 2021 Feb 10.
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Diabetes Technol Ther. 2021 Jul;23(7):491-499. doi: 10.1089/dia.2020.0618. Epub 2021 Feb 26.
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Impact of Hybrid Closed Loop Therapy on Hypoglycemia Awareness in Individuals with Type 1 Diabetes and Impaired Hypoglycemia Awareness.1 型糖尿病合并低血糖感知受损患者的混合闭环治疗对低血糖感知的影响。
Diabetes Technol Ther. 2021 Jul;23(7):482-490. doi: 10.1089/dia.2020.0593.
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Predictive Low-Glucose Suspend Necessitates Less Carbohydrate Supplementation to Rescue Hypoglycemia: Need to Revisit Current Hypoglycemia Treatment Guidelines.预测性低血糖暂停需要更少的碳水化合物补充来抢救低血糖：需要重新审视当前的低血糖治疗指南。
Diabetes Technol Ther. 2021 Jul;23(7):512-516. doi: 10.1089/dia.2020.0619. Epub 2021 Feb 18.