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以喉上神经麻痹为表现的吸入性有机磷中毒:1例罕见病例

Inhaled Organophosphorus Poisoning Presenting as Superior Laryngeal Nerve Palsy: A Rare Case.

作者信息

Patel Sujal, Patel Mansi, Hande Vaidehi, Jain Shraddha, Kumar Sunil, Acharya Sourya

机构信息

Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Department of Otolaryngology - Head and Neck Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

出版信息

Cureus. 2022 Nov 16;14(11):e31589. doi: 10.7759/cureus.31589. eCollection 2022 Nov.

DOI:10.7759/cureus.31589
PMID:36540451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9757641/
Abstract

Poisoning by organophosphorus (OP) is a major clinical issue affecting many nations worldwide, especially developing nations. In this case report, we have highlighted organophosphate poisoning syndrome that resulted in paralysis of the vocal cords. A 28-year-old male patient with a history of accidental inhalation of the OP compound reported to our hospital with symptoms of vomiting and hoarseness of voice. He had nasal regurgitation and hoarseness having both 9th and 10th cranial nerve palsies on admission, which improved after administration of atropine.

摘要

有机磷中毒是一个影响全球许多国家,尤其是发展中国家的重大临床问题。在本病例报告中,我们着重介绍了导致声带麻痹的有机磷中毒综合征。一名有意外吸入有机磷化合物病史的28岁男性患者因呕吐和声音嘶哑症状前来我院就诊。入院时,他出现鼻反流和声音嘶哑,伴有第9和第10对颅神经麻痹,使用阿托品治疗后症状有所改善。

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本文引用的文献

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Platypnea-orthodeoxia syndrome: A dangerous detour of intermediate syndrome with organophosphorus poisoning.平卧呼吸-直立性低氧血症综合征:有机磷中毒中间综合征的危险弯路。
J Family Med Prim Care. 2022 Jul;11(7):4074-4078. doi: 10.4103/jfmpc.jfmpc_2357_21. Epub 2022 Jul 22.
2
Intermediate Syndrome and Marchiafava-Bignami Syndrome: Double Trouble in Weaning Off.中间综合征和马奇亚法瓦-比尼亚米综合征:撤机过程中的双重麻烦。
Cureus. 2022 Jul 9;14(7):e26694. doi: 10.7759/cureus.26694. eCollection 2022 Jul.
3
Myocardial infarction in organophosphorus poisoning: Association or just chance?
有机磷中毒中的心肌梗死:是关联还是纯属巧合?
J Emerg Trauma Shock. 2014 Apr;7(2):131-2. doi: 10.4103/0974-2700.130885.
4
Delayed onset neuropathy along with recurrent laryngeal nerve palsy due to organophosphate poisoning and the role of physiotherapy rehabilitation.有机磷中毒所致迟发性神经病伴喉返神经麻痹及物理治疗康复的作用
Indian J Crit Care Med. 2014 Feb;18(2):102-4. doi: 10.4103/0972-5229.126082.
5
Isolated bilateral vocal cord paralysis with intermediate syndrome after organophosphate poisoning.有机磷中毒后出现中间综合征伴孤立性双侧声带麻痹。
Clin Toxicol (Phila). 2008 Jun;46(5):482-4. doi: 10.1080/15563650701704842.
6
Brief bilateral vocal cord paralysis after insecticide poisoning. A new variant of toxicity syndrome.杀虫剂中毒后短暂性双侧声带麻痹。一种新的毒性综合征变体。
Arch Otolaryngol Head Neck Surg. 1997 Jan;123(1):93-6. doi: 10.1001/archotol.1997.01900010103016.
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Neurotoxic effects of organophosphorus insecticides. An intermediate syndrome.有机磷杀虫剂的神经毒性作用。中间综合征。
N Engl J Med. 1987 Mar 26;316(13):761-3. doi: 10.1056/NEJM198703263161301.