Wu Adela, Zhou James, Quinlan Nicky, Dirlikov Benjamin, Singh Harminder
Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
California Northstate University College of Medicine, Elk Grove, CA 95757, United States.
J Clin Neurosci. 2023 Feb;108:1-5. doi: 10.1016/j.jocn.2022.12.013. Epub 2022 Dec 19.
We identified factors and outcomes associated with inpatient palliative care (PC) consultation, stratified into early and late timing, for patients over age 65 with traumatic brain injuries (TBI). Patients over age 65 presenting to a single institution with TBI and intracranial hemorrhage from January 2013-September 2020 were included. Patient demographics and various outcomes were analyzed. Inpatient PC consultation was uncommon (4 % out of 576 patients). Characteristics associated with likelihood of consultation were severe TBI (OR = 5.030, 95 % CI 1.096-23.082, p =.038) and pre-existing dementia (OR = 6.577, 95 % CI 1.726-25.073, p =.006). Average consultation timing was 8.6 (standard deviation ± 7.0) days. Patients with PC consults had longer overall (p =.0031) and intensive care unit (ICU) length of stays (LOS) (p <.0001), more days intubated (p <.0001) and higher costs (p =.0006), although those with earlier-than-average PC consultation had shorter overall (p =.0062) and ICU (p =.011) LOS as well as fewer ventilator days (p =.030) and lower costs (p =.0003). Older patients with TBI are more likely to receive PC based on pre-existing dementia and severe TBI. Patients with PC consultations had worse LOS and higher costs. However, these effects were mitigated by earlier PC involvement. Our study emphasizes the need for timely PC consultation in a vulnerable patient population.
我们确定了与65岁以上创伤性脑损伤(TBI)患者住院姑息治疗(PC)会诊相关的因素和结果,并根据会诊时间早晚进行了分层。纳入了2013年1月至2020年9月期间在单一机构就诊的65岁以上患有TBI和颅内出血的患者。分析了患者的人口统计学特征和各种结果。住院PC会诊并不常见(576例患者中占4%)。与会诊可能性相关的特征包括重度TBI(OR = 5.030,95%CI 1.096 - 23.082,p = 0.038)和既往痴呆症(OR = 6.577,95%CI 1.726 - 25.073,p = 0.006)。平均会诊时间为8.6(标准差±7.0)天。接受PC会诊的患者总体住院时间(p = 0.0031)和重症监护病房(ICU)住院时间(LOS)更长(p < 0.0001),插管天数更多(p < 0.0001),费用更高(p = 0.0006),不过会诊时间早于平均水平的患者总体住院时间(p = 0.0062)和ICU住院时间(p = 0.011)更短,呼吸机使用天数更少(p = 0.030),费用更低(p = 0.0003)。患有TBI的老年患者基于既往痴呆症和重度TBI更有可能接受PC治疗。接受PC会诊的患者住院时间更长,费用更高。然而,早期PC介入减轻了这些影响。我们的研究强调了在脆弱患者群体中及时进行PC会诊的必要性。