Yu Catherine, Lokan Julie, Jackett Louise, Nikfarjam Mehrdad, Mills Christopher
General Medicine, Austin Health, Melbourne, Victoria, Australia
Pathology, Austin Health, Melbourne, Victoria, Australia.
BMJ Case Rep. 2022 Dec 22;15(12):e246398. doi: 10.1136/bcr-2021-246398.
A man aged above 70 years old with a medical history of ulcerative colitis presented with unintentional weight loss. A pancreatic mass associated with pancreatic duct dilatation was detected on imaging procedures. Initial investigations including fine needle aspiration and cytology examination were inconclusive. A diagnosis of intraductal tubulopapillary neoplasm (ITPN) was made with histopathology and immunohistochemistry examination on a surgically resected specimen. Two years after surgery, the patient remained well with no radiological evidence of recurrence.ITPN is a rare pancreatic duct tumour with limited case reports in medical literature. Risk factors are not well established. We report the first case of ITPN occurring in a patient with ulcerative colitis. A typical presentation of this rare tumour is reported to encourage clinicians to consider ITPN in the differential diagnoses of a pancreatic mass.
一名70岁以上有溃疡性结肠炎病史的男性出现非故意体重减轻。影像学检查发现胰腺肿块伴胰管扩张。包括细针穿刺和细胞学检查在内的初步检查结果不明确。通过对手术切除标本进行组织病理学和免疫组织化学检查，诊断为导管内管状乳头状肿瘤（ITPN）。术后两年，患者情况良好，无复发的影像学证据。ITPN是一种罕见的胰腺导管肿瘤，医学文献中的病例报告有限。危险因素尚未明确确立。我们报告了首例发生在溃疡性结肠炎患者中的ITPN。报告了这种罕见肿瘤的典型表现，以鼓励临床医生在胰腺肿块的鉴别诊断中考虑ITPN。
