Acupuncture and Moxibustion School Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
State Key Laboratory of Oral Disease and National Clinical Research Center for Oral Diseases and Department of Oral Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Medicine (Baltimore). 2022 Dec 16;101(50):e32251. doi: 10.1097/MD.0000000000032251.
Herpes zoster and post-herpetic neuralgia showed an increasing incidence during past two decades. Most of herpes zoster and post-herpetic neuralgia patients suffered from pain, anxiety, and depression. Fire needle combined with cupping is becoming a popular way to relieve the pain caused by herpes zoster and decrease the incidence of post-herpetic neuralgia. In this study, we aim to investigating the efficacy and safety of fire needle combined with cupping for the treatment of acute herpes zoster and postherpetic neuralgia (PHN).
The literature search will be carried out in following databases: PubMed/MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, Chinese Biomedical Literature Database and Wanfang Data. Published and unpublished controlled trials compared fire needle combined with cupping to other treatments for acute herpes zoster or PHN will be included. Data from eligible studies will be extracted by 2 independent reviewers. Different scales will be used to assess the risk of bias based on the study design. Pain intensity and PHN are primary outcomes. The final effect size will be reported using 95% confidence interval at 0.05 significance level.
This review will provide certain evidence to compare the efficacy and safety of combined acupuncture and cupping with guideline recommended drug or nerve block therapy for the treatment of herpes zoster and post-herpetic neuralgia. It will potentially provide more clinical suggestions and guidelines for health care professionals, policymakers, and researchers.
在过去的二十年中，带状疱疹和带状疱疹后神经痛的发病率呈上升趋势。大多数带状疱疹和带状疱疹后神经痛患者都遭受疼痛、焦虑和抑郁的困扰。火针结合拔罐正成为缓解带状疱疹引起的疼痛和降低带状疱疹后神经痛发生率的一种流行方法。在这项研究中，我们旨在研究火针结合拔罐治疗急性带状疱疹和带状疱疹后神经痛（PHN）的疗效和安全性。
将在以下数据库中进行文献检索：PubMed/MEDLINE、EMBASE、Cochrane 中央对照试验注册库、中国国家知识基础设施、中国生物医学文献数据库和万方数据。将纳入比较火针结合拔罐与其他治疗急性带状疱疹或 PHN 的治疗方法的已发表和未发表的对照试验。由 2 名独立评审员提取合格研究的数据。根据研究设计，使用不同的量表评估偏倚风险。疼痛强度和 PHN 是主要结局。最终效应大小将在 0.05 显著性水平下使用 95%置信区间报告。
本综述将为比较联合针刺和拔罐与指南推荐的药物或神经阻滞疗法治疗带状疱疹和带状疱疹后神经痛的疗效和安全性提供一定证据。它可能为医疗保健专业人员、政策制定者和研究人员提供更多的临床建议和指南。
