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利用辣根过氧化物酶的运输追踪从股隐静脉到背根神经节的传入通路。

Tracing of afferent pathways from the femoral-saphenous vein to the dorsal root ganglia using transport of horseradish peroxidase.

作者信息

Yates B J, Mickle J P, Hedden W J, Thompson F J

机构信息

Department of Neuroscience, College of Veterinary Medicine, University of Florida, Gainesville 32610.

出版信息

J Auton Nerv Syst. 1987 Jul;20(1):1-11. doi: 10.1016/0165-1838(87)90076-2.

DOI:10.1016/0165-1838(87)90076-2
PMID:3655181
Abstract

The retrograde transport of horseradish peroxidase (HRP) was used to trace afferents from the femoral-saphenous vein to the dorsal root ganglia in the cat. Afferents arising along the entire length of the vein projected to very localized spinal levels; 63% of the labeled cells counted were located in the L6 dorsal root ganglion, 37% were located in the L5 ganglion and less than 1% were located at other levels. Most of the cell bodies labeled by the application of HRP to the femoral-saphenous vein were small in size (diameter less than 35 microns). However, some large cell bodies (diameter greater than 50 microns) were also noted. It was estimated that over two-thirds of the femoral-saphenous venous afferents were C fibers; at least 15% were estimated to be A fibers. The largest venous afferents were predicted to conduct action potentials at approximately 60 m/s.

摘要

利用辣根过氧化物酶(HRP)逆行运输法追踪猫股隐静脉至背根神经节的传入纤维。沿静脉全长发出的传入纤维投射至非常局限的脊髓节段;计数的标记细胞中63%位于L6背根神经节,37%位于L5神经节,不到1%位于其他节段。将HRP应用于股隐静脉标记的大多数细胞体体积较小(直径小于35微米)。然而,也观察到一些大的细胞体(直径大于50微米)。据估计,超过三分之二的股隐静脉传入纤维是C纤维;估计至少15%是A纤维。预计最大的静脉传入纤维以约60米/秒的速度传导动作电位。

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