Baumann R J, Carr W A, Shuman R M
Department of Neurology, University of Kentucky, Lexington 40536-0084.
J Child Neurol. 1987 Oct;2(4):298-306. doi: 10.1177/088307388700200413.
We reviewed the data from 215 consecutively imaged children who were referred because of neurologic disease. We specifically looked for evidence of cerebral arterial infarction in the form of focal brain damage in an arterial vascular distribution. Twenty-eight showed an arterial infarction pattern. All the major cerebral arteries were involved: middle cerebral artery, 17/28; posterior cerebral artery, 7/28; anterior cerebral artery, 2/28; carotid, 2/28; and vertebro-basilar, 1/28. Six of the 28 subjects had disorders reported to be associated with cerebrovascular damage. Another 13 subjects had other associated disorders, including perinatal distress and presumed anoxia, closed head trauma, hydrocephalus, and dehydration with electrolyte imbalance. Despite a careful search of medical records, we were unable to find any evidence of an adverse event or associated illness for more than one third of the children. These data suggest that cerebral arterial infarction is a more common lesion in the static neurologic disabilities of childhood than previously thought.
我们回顾了215例因神经系统疾病而接受连续影像学检查的儿童的数据。我们特别寻找以动脉血管分布区域的局灶性脑损伤形式存在的脑动脉梗死证据。28例显示出动脉梗死模式。所有主要脑动脉均受累:大脑中动脉,17/28;大脑后动脉,7/28;大脑前动脉,2/28;颈动脉,2/28;椎基底动脉,1/28。28名受试者中有6名患有据报道与脑血管损伤相关的疾病。另外13名受试者有其他相关疾病,包括围产期窘迫和疑似缺氧、闭合性头部外伤、脑积水以及伴有电解质失衡的脱水。尽管仔细查阅了病历,但我们仍无法找到超过三分之一儿童存在不良事件或相关疾病的任何证据。这些数据表明,脑动脉梗死在儿童静态神经功能障碍中是一种比以前认为的更为常见的病变。