Borzage Matthew T, Doyle Eamon K, Liu Chia-Shang J, Nelson Marvin D, Blüml Stefan, Wood John C, Tamrazi Benita
Department of Pediatrics, Children's Hospital of Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA.
Department of Radiology, Children's Hospital of Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA.
Diagnostics (Basel). 2022 Nov 26;12(12):2962. doi: 10.3390/diagnostics12122962.
Quantitative susceptibility mapping (QSM) is an MRI-based technique for iron quantification of targeted tissue. QSM provides information relevant to clinicians in a broad range of diagnostic contexts, including sickle cell disease, inflammatory/demyelinating processes, and neoplasms. However, major MRI vendors do not offer QSM post-processing in a form ready for general use. This work describes a vendor-agnostic approach for scaling QSM analysis from a research technique to a routine diagnostic test. We provide the details needed to seamlessly integrate hardware, software, and clinical systems to provide QSM processing for a busy clinical radiology workflow. This approach can be generalized to other advanced MRI acquisitions and analyses with proven diagnostic utility, yet without crucial MR vendor support.
定量磁化率成像（QSM）是一种基于磁共振成像（MRI）的技术，用于对目标组织进行铁定量分析。QSM在广泛的诊断环境中为临床医生提供相关信息，包括镰状细胞病、炎症/脱髓鞘过程和肿瘤。然而，主要的MRI设备供应商并未以可供普遍使用的形式提供QSM后处理功能。这项工作描述了一种与供应商无关的方法，用于将QSM分析从研究技术扩展为常规诊断测试。我们提供了无缝集成硬件、软件和临床系统所需的详细信息，以便为繁忙的临床放射学工作流程提供QSM处理。这种方法可以推广到其他具有已证实诊断效用的先进MRI采集和分析中，而无需关键的MR设备供应商支持。
