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Systemic Lymphadenopathic Mastocytosis with Eosinophilia.

作者信息

Im Soyoung, Kim Jeong-A, Park Gyeongsin, Cho Uiju

机构信息

Department of Pathology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

出版信息

Diagnostics (Basel). 2022 Dec 6;12(12):3057. doi: 10.3390/diagnostics12123057.

DOI:10.3390/diagnostics12123057
PMID:36553063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9776443/
Abstract

Systemic mastocytosis is a neoplastic proliferation of mast cells that most frequently involves cutaneous sites. Mastocytosis involves various extracutaneous sites, but the lymph node is rare. We present an interesting image of systemic mastocytosis in the lymph node with marked eosinophilia. It is a rare subtype of systemic mastocytosis requiring high suspicion levels for the correct diagnosis.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aff/9776443/2656a438c920/diagnostics-12-03057-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aff/9776443/9d57bf545874/diagnostics-12-03057-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aff/9776443/2656a438c920/diagnostics-12-03057-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aff/9776443/9d57bf545874/diagnostics-12-03057-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aff/9776443/2656a438c920/diagnostics-12-03057-g002.jpg

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本文引用的文献

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Clinical impact and proposed application of molecular markers, genetic variants, and cytogenetic analysis in mast cell neoplasms: Status 2022.在肥大细胞肿瘤中分子标志物、遗传变异和细胞遗传学分析的临床影响及建议应用:2022 现状。
J Allergy Clin Immunol. 2022 Jun;149(6):1855-1865. doi: 10.1016/j.jaci.2022.04.004. Epub 2022 Apr 14.
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Am J Hematol. 2021 Apr 1;96(4):508-525. doi: 10.1002/ajh.26118. Epub 2021 Feb 21.
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Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1.伴有嗜酸性粒细胞增多以及PDGFRA、PDGFRB或FGFR1异常的髓系和淋系肿瘤
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Lymph node findings in generalized mastocytosis.
Histopathology. 1992 Nov;21(5):439-46. doi: 10.1111/j.1365-2559.1992.tb00428.x.