Schleder Stephan, May Matthias, Habicher Werner, Dinkel Johannes, Schreyer Andreas G, Gostian Antoniu-Oreste, Schicho Andreas
Department of Diagnostic and Interventional Radiology, Merciful Brothers Hospital St. Elisabeth, 94315 Straubing, Germany.
Department of Urology, Merciful Brothers Hospital St. Elisabeth, 94315 Straubing, Germany.
Diagnostics (Basel). 2022 Dec 16;12(12):3200. doi: 10.3390/diagnostics12123200.
(1) Background: Early-stage glottic cancer is easily missed on magnetic resonance imaging (MRI). Diffusion-weighted imaging (DWI) may improve diagnostic accuracy. Therefore, our aim was to assess the value of adding diffusion-weighted imaging with background body signal suppression (DWIBS) to pre-therapeutic MRI staging. (2) Methods: Two radiologists with 8 and 13 years of experience, blinded to each other's findings, initially interpreted only standard MRI, later DWIBS alone, and afterward, standard MRI + DWIBS in 41 patients with histopathologically proven pT1a laryngeal cancer of the glottis. (3) Results: Detectability rates with standard MRI, DWIBS only, and standard MRI + DWIBS were 68-71%, 63-66%, and 73-76%, respectively. Moreover, interobserver reliability was calculated as good (κ = 0.712), very good (κ = 0.84), and good (κ = 0.69) for standard MRI, DWIBS only, and standard MRI + DWIBS, respectively. (4) Conclusions: Standard MRI, DWIBS alone, and standard MRI + DWIBS showed an encouraging detection rate, as well as distinct interobserver reliability in the diagnosis of early-stage laryngeal cancer when compared to the definitive histopathologic report.
(1) 背景：早期声门癌在磁共振成像（MRI）上容易被漏诊。扩散加权成像（DWI）可能会提高诊断准确性。因此，我们的目的是评估在治疗前MRI分期中增加背景体部信号抑制扩散加权成像（DWIBS）的价值。(2) 方法：两名分别具有8年和13年经验的放射科医生，彼此不知道对方的诊断结果，最初仅解读标准MRI，之后仅解读DWIBS，最后解读41例经组织病理学证实为声门型pT1a喉癌患者的标准MRI + DWIBS。(3) 结果：标准MRI、仅DWIBS以及标准MRI + DWIBS的检出率分别为68 - 71%、63 - 66%和73 - 76%。此外，标准MRI、仅DWIBS以及标准MRI + DWIBS的观察者间可靠性计算结果分别为良好（κ = 0.712）、非常好（κ = 0.84）和良好（κ = 0.69）。(4) 结论：与最终的组织病理学报告相比，标准MRI、单独的DWIBS以及标准MRI + DWIBS在早期喉癌诊断中显示出令人鼓舞的检出率以及明显的观察者间可靠性。
