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早期病变术前经口激光显微手术及放射治疗相关的高分辨率喉部磁共振成像的改进

Improvements in High Resolution Laryngeal Magnetic Resonance Imaging for Preoperative Transoral Laser Microsurgery and Radiotherapy Considerations in Early Lesions.

作者信息

Ruytenberg Thomas, Verbist Berit M, Vonk-Van Oosten Jordi, Astreinidou Eleftheria, Sjögren Elisabeth V, Webb Andrew G

机构信息

C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands.

Department of Radiology, Leiden University Medical Center, Leiden, Netherlands.

出版信息

Front Oncol. 2018 Jun 6;8:216. doi: 10.3389/fonc.2018.00216. eCollection 2018.

Abstract

As the benefits, limitations, and contraindications of transoral laser microsurgery (TLM) in glottic carcinoma treatments become better defined, pretreatment imaging has become more important to assess the case-specific suitability of TLM and to predict functional outcomes both for treatment consideration and patient counseling. Magnetic resonance imaging (MRI) is the preferred modality to image such laryngeal tumors, even though imaging the larynx using MRI can be difficult. The first challenge is that there are no commercial radiofrequency (RF) coils that are specifically designed for imaging the larynx, and performance in terms of coverage and signal-to-noise ratio is compromised using general-purpose RF coils. Second, motion in the neck region induced by breathing, swallowing, and vessel pulsation can induce severe image artifacts, sometimes rendering the images unusable. In this paper, we design a dedicated RF coil array, which allows high quality high-resolution imaging of the larynx. In addition, we show that introducing respiratory-triggered acquisition improves the diagnostic quality of the images by minimizing breathing and swallowing artifacts. Together, these developments enable robust, essentially artifact-free images of the full larynx with an isotropic resolution of 1 mm to be acquired within a few minutes.

摘要

随着经口激光显微手术(TLM)在声门癌治疗中的益处、局限性和禁忌症越来越明确,术前成像对于评估TLM的病例特异性适用性以及预测功能结果以用于治疗考量和患者咨询变得更加重要。磁共振成像(MRI)是对这类喉部肿瘤进行成像的首选方式,尽管使用MRI对喉部成像可能具有挑战性。第一个挑战是没有专门为喉部成像设计的商业射频(RF)线圈,使用通用RF线圈在覆盖范围和信噪比方面的性能会受到影响。其次,呼吸、吞咽和血管搏动在颈部区域引起的运动可导致严重的图像伪影,有时会使图像无法使用。在本文中,我们设计了一种专用RF线圈阵列,可实现喉部的高质量高分辨率成像。此外,我们表明引入呼吸触发采集可通过最小化呼吸和吞咽伪影来提高图像的诊断质量。这些进展共同使得能够在几分钟内获取全喉的稳健、基本无伪影且各向同性分辨率为1毫米的图像。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aa6/5997776/b0520acf4827/fonc-08-00216-g001.jpg

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