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免疫功能正常患者中由产POM-1金属β-内酰胺酶引起的附睾炎-睾丸炎:病例报告及分子特征分析

Epididymo-Orchitis Caused by POM-1 Metallo-β-Lactamase-Producing in an Immunocompetent Patient: Case Report and Molecular Characterization.

作者信息

Alqurashi Moayad, Alsaedy Abdulrahman, Alalwan Bassam, Alzayer Maha, Alswaji Abdulrahman, Okdah Liliane, Doumith Michel, Zowawi Hosam, Aljohani Sameera, Alghoribi Majed

机构信息

Department of Medicine, King Abdulaziz Medical City, Ministry of the National Guard-Health Affairs, Riyadh 11426, Saudi Arabia.

Division of Adult Infectious Diseases, Department of Medicine, King Abdulaziz Medical City, Ministry of the National Guard-Health Affairs, Riyadh 11426, Saudi Arabia.

出版信息

Pathogens. 2022 Dec 5;11(12):1475. doi: 10.3390/pathogens11121475.

Abstract

is a rare and unique species among the genus that has not been previously reported as a cause of male genitourinary tract infection. In this report, we describe a case of a 20-year-old immunocompetent male who presented with recurrent epididymo-orchitis, which was initially misidentified as Vibrio vulnificus and treated successfully. The causative agent could not be identified appropriately using the available routine methods, but a final identification was established using 16S rRNA targeted sequencing followed by whole-genome sequencing.

摘要

是该属中一种罕见且独特的物种,此前尚未有作为男性泌尿生殖道感染病因的报道。在本报告中,我们描述了一例20岁免疫功能正常男性反复出现附睾炎-睾丸炎的病例,该病例最初被误诊为创伤弧菌并成功治愈。使用现有的常规方法无法正确鉴定病原体,但通过16S rRNA靶向测序,随后进行全基因组测序确定了最终鉴定结果。

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