From the Department of Radiology, University of Florida College of Medicine-Jacksonville, Jacksonville, FL.
Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL.
Clin Nucl Med. 2023 Feb 1;48(2):201-202. doi: 10.1097/RLU.0000000000004499. Epub 2022 Dec 7.
Nasopharyngeal carcinoma (NC) is an epithelial tumor with distinctive prevalence in East and Southeast Asia. Most patients with NC only experience regional metastasis. In cases of distant metastasis, prognosis is grim. Leptomeningeal spread of the disease is a rare occurrence, which is sparsely described in the literature. We present a case of a 33-year-old man with a history of high-grade NC with leptomeningeal metastasis. Initial MRI lumbar spine demonstrated subtle findings consistent with leptomeningeal disease. These findings are easily discernible on 18 F-FDG PET/CT.
鼻咽癌（NC）是一种上皮性肿瘤，在东亚和东南亚地区具有独特的流行率。大多数 NC 患者仅经历区域性转移。发生远处转移时，预后较差。脑膜播散是一种罕见的疾病，文献中描述较少。我们报告了一例 33 岁男性，患有高级别 NC 和脑膜转移病史。腰椎 MRI 最初显示符合脑膜疾病的细微发现。这些发现在 18 F-FDG PET/CT 上很容易识别。
