Layfield L J, Mukamel E, Hilborne L H, Hannah J B, Glasgow B J, Ljung B M, deKernion J B
Department of Pathology, University of California, Los Angeles Medical Center.
J Urol. 1987 Oct;138(4):798-800. doi: 10.1016/s0022-5347(17)43378-7.
Cytological grade determined by fine needle aspiration of the prostate was compared to histological grade in 30 patients undergoing subsequent radical prostatectomy. The degree of cytological pleomorphism determined by the consensus grade of 3 observers predicted correctly the Gleason grade sum range in 80 per cent of the cases. The cytological grade was reasonably reproducible with agreement among all 3 observers in 50 per cent of the cases and between 2 of 3 observers in the remainder. The accuracy of predicting the Gleason grade sum of the radical prostatectomy specimen by cytological examination compared favorably with that achieved by histological examination of cutting needle biopsy and transurethral resection specimens reported in the literature.
对30例随后接受根治性前列腺切除术的患者，将经前列腺细针穿刺确定的细胞学分级与组织学分级进行比较。由3名观察者的共识分级所确定的细胞学多形性程度在80%的病例中正确预测了Gleason分级总和范围。在50%的病例中，所有3名观察者之间的细胞学分级具有合理的可重复性，其余病例中3名观察者中有2名之间的分级具有可重复性。与文献报道的通过切割针活检和经尿道切除标本的组织学检查所达到的准确性相比，通过细胞学检查预测根治性前列腺切除标本的Gleason分级总和的准确性更优。
