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细菌黏附动力学——一项随机分析

Kinetics of bacterial adhesion--a stochastic analysis.

作者信息

Hsu J P, Wang H H

机构信息

Department of Chemical Engineering, National Taiwan University, Taipei, R.O.C.

出版信息

J Theor Biol. 1987 Feb 21;124(4):405-13. doi: 10.1016/s0022-5193(87)80218-7.

Abstract

In a previous work (Hsu & Wang, 1986), a birth-death type of stochastic model was proposed to analyze bacterial adhesion onto the substrate surface. The model is based upon the assumption that the number of available active sites on the substrate surface is relatively large compared to that of the cells in the system. This assumption is relaxed in the present study, and thus, the problem is considered in a more rigorous manner. The transient behavior of bacterial adhesion is examined through simulation studies. It is found that the present stochastic model should be employed when the number of available active sites is less than or on the same order of magnitude as that of the cells.

摘要

在之前的一项工作中(许和王,1986年),提出了一种生死型随机模型来分析细菌在底物表面的黏附。该模型基于这样一个假设:与系统中的细胞数量相比,底物表面可用的活性位点数量相对较多。在本研究中,这个假设被放宽了,因此,以更严谨的方式考虑该问题。通过模拟研究考察了细菌黏附的瞬态行为。发现当可用活性位点的数量小于细胞数量或与细胞数量处于同一数量级时,应采用当前的随机模型。

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