Inflammatory Bowel Disease Center, Yokohama City University Medical Center, Japan.
Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Japan.
Intern Med. 2023 Aug 15;62(16):2341-2348. doi: 10.2169/internalmedicine.0839-22. Epub 2022 Dec 28.
Pregnancy is a known risk factor for amebic enteritis, which develops into potentially fatal fulminant amebic enteritis in some cases. We describe a case of a 27-year-old non-immunosuppressed pregnant woman with fulminant amebic enteritis complicated with cytomegalovirus enteritis. She improved with intensive care and intravenous metronidazole and ganciclovir but eventually required subtotal colectomy for intestinal stenosis. It is difficult to diagnose amebic enteritis, especially in a non-endemic area. Amebic enteritis must be considered as a differential diagnosis for refractory diarrhea with bloody stools in women in the perinatal period, even those without immunosuppression.
妊娠是阿米巴性肠炎的已知危险因素,在某些情况下,该病可发展为潜在致命的暴发性阿米巴性肠炎。我们描述了一例 27 岁非免疫抑制的孕妇患有暴发性阿米巴性肠炎合并巨细胞病毒肠炎。她通过重症监护和静脉用甲硝唑和更昔洛韦治疗后有所改善,但最终因肠狭窄需要进行次全结肠切除术。阿米巴性肠炎的诊断较为困难,特别是在非流行地区。对于围产期有难治性腹泻伴血便的女性,即使没有免疫抑制,也应考虑将阿米巴性肠炎作为鉴别诊断。