当前流行的猴痘病毒的药物敏感性 - Suppr

Drug Sensitivity of Currently Circulating Mpox Viruses.

作者信息

Bojkova Denisa, Bechtel Marco, Rothenburger Tamara, Steinhorst Katja, Zöller Nadja, Kippenberger Stefan, Schneider Julia, Corman Victor M, Uri Hannah, Wass Mark N, Knecht Gaby, Khaykin Pavel, Wolf Timo, Ciesek Sandra, Rabenau Holger F, Michaelis Martin, Cinatl Jindrich

机构信息

University Hospital, Frankfurt am Main, Germany.

Charité-Universitätsmedizin, Berlin, Germany.

出版信息

N Engl J Med. 2023 Jan 19;388(3):279-281. doi: 10.1056/NEJMc2212136. Epub 2022 Dec 28.

DOI:10.1056/NEJMc2212136

PMID:36577096

Abstract

摘要

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引用本文的文献

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Drug Sensitivity of Currently Circulating Mpox Viruses.

作者信息

机构信息

University Hospital, Frankfurt am Main, Germany.

Charité-Universitätsmedizin, Berlin, Germany.

出版信息

N Engl J Med. 2023 Jan 19;388(3):279-281. doi: 10.1056/NEJMc2212136. Epub 2022 Dec 28.

DOI:10.1056/NEJMc2212136

PMID:36577096

Abstract

摘要

相似文献

Drug Sensitivity of Currently Circulating Mpox Viruses.

N Engl J Med. 2023 Jan 19;388(3):279-281. doi: 10.1056/NEJMc2212136. Epub 2022 Dec 28.

Inhibition of cowpox virus and monkeypox virus infection by mitoxantrone.

Antiviral Res. 2012 Feb;93(2):305-308. doi: 10.1016/j.antiviral.2011.12.001. Epub 2011 Dec 11.

Antivirals With Activity Against Mpox: A Clinically Oriented Review.

Clin Infect Dis. 2023 Jan 6;76(1):155-164. doi: 10.1093/cid/ciac622.

Characterization of wild-type and cidofovir-resistant strains of camelpox, cowpox, monkeypox, and vaccinia viruses.

Antimicrob Agents Chemother. 2002 May;46(5):1329-35. doi: 10.1128/AAC.46.5.1329-1335.2002.

Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection.

Nature. 2006 Feb 9;439(7077):745-8. doi: 10.1038/nature04295. Epub 2005 Dec 11.

ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification.

Antimicrob Agents Chemother. 2009 May;53(5):1817-22. doi: 10.1128/AAC.01596-08. Epub 2009 Feb 17.

Monkeypox virus induces the synthesis of less dsRNA than vaccinia virus, and is more resistant to the anti-poxvirus drug, IBT, than vaccinia virus.

Virology. 2016 Oct;497:125-135. doi: 10.1016/j.virol.2016.07.016. Epub 2016 Jul 26.

Can a smallpox drug treat monkeypox? Here's what scientists know.

Nature. 2022 Sep;609(7927):451-452. doi: 10.1038/d41586-022-02245-2.

Pharmacokinetic and pharmacodynamic modeling to determine the dose of ST-246 to protect against smallpox in humans.

Antimicrob Agents Chemother. 2013 Mar;57(3):1136-43. doi: 10.1128/AAC.00959-12. Epub 2012 Dec 17.

Hopes dashed for drug aimed at monkeypox virus spreading in Africa.

Nature. 2024 Aug;632(8027):965. doi: 10.1038/d41586-024-02694-x.

引用本文的文献

Novel derivatives of brincidofovir and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine inhibit orthopoxviruses and human adenoviruses more potently than brincidofovir.

Signal Transduct Target Ther. 2025 Apr 11;10(1):114. doi: 10.1038/s41392-025-02207-w.

Monkeypox Virus: WHO's Second Public Health Emergency of International Concern Within 2 Years.

Microb Biotechnol. 2025 Apr;18(4):e70142. doi: 10.1111/1751-7915.70142.

Lessons for medical countermeasure development from unforeseen outbreaks.

Emerg Microbes Infect. 2025 Dec;14(1):2471035. doi: 10.1080/22221751.2025.2471035. Epub 2025 Mar 10.

Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges.

Curr Oncol Rep. 2025 Mar;27(3):195-210. doi: 10.1007/s11912-025-01635-9. Epub 2025 Feb 6.

MedComm (2020). 2024 Aug 4;5(8):e677. doi: 10.1002/mco2.677. eCollection 2024 Aug.

Multiple introductions of monkeypox virus to Ireland during the international mpox outbreak, May 2022 to October 2023.

Euro Surveill. 2024 Apr;29(16). doi: 10.2807/1560-7917.ES.2024.29.16.2300505.

Surveillance of Complicated Mpox Cases Unresponsive to Oral Tecovirimat in Los Angeles County, 2022.

J Infect Dis. 2024 Mar 26;229(Supplement_2):S249-S254. doi: 10.1093/infdis/jiad517.

Tecovirimat Resistance in Mpox Patients, United States, 2022-2023.

Emerg Infect Dis. 2023 Dec;29(12):2426-2432. doi: 10.3201/eid2912.231146. Epub 2023 Oct 19.

In vitro susceptibility of eighteen clinical isolates of human monkeypox virus to tecovirimat.

Mem Inst Oswaldo Cruz. 2023 Jul 10;118:e230056. doi: 10.1590/0074-02760230056. eCollection 2023.

Potential therapeutic targets for Mpox: the evidence to date.

Expert Opin Ther Targets. 2023 Jan-Jun;27(6):419-431. doi: 10.1080/14728222.2023.2230361. Epub 2023 Jul 4.

Drug Sensitivity of Currently Circulating Mpox Viruses.

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Drug Sensitivity of Currently Circulating Mpox Viruses.

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