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高危临床青少年中睡眠障碍与自我伤害行为之间的关系。

The relationship between sleep disturbance and self-harming behaviours in high-risk clinical adolescents.

作者信息

Nguyen Thomas P, Lerch Stefan, Maggetti Alessia, Reichl Corinna, Tarokh Leila, Kaess Michael

机构信息

Mental Health, School of Medicine, Western Sydney University, Sydney, Australia; University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

出版信息

J Psychiatr Res. 2023 Feb;158:81-87. doi: 10.1016/j.jpsychires.2022.12.034. Epub 2022 Dec 21.

Abstract

Emerging research has identified sleep disturbance as an important risk factor for predicting self-harming behaviours. However, the temporality of this relationship, particularly in clinical adolescent samples remains poorly understood. This study examines the relationship between sleep disturbance and self-harming behaviours (namely nonsuicidal self-injury and suicide attempts) in clinical adolescents engaging in risk-taking and self-harming behaviours using secondary analyses from a clinical cohort study. Cross-lagged structural equation modelling was used to determine whether baseline sleep disturbance and self-harming behaviours were predictors of each other over a one-year follow-up period in a sample of adolescents (n = 238, 89.5% female) attending and receiving treatment from an outpatient clinic specializing in risk-taking and self-harming behaviours. When controlling for age, sex and depressive symptoms, greater sleep disturbance (p = 0.001) at baseline independently predicted higher numbers of suicide attempts at follow-up. No bidirectional relationship was found when sleep disturbance was modelled with the frequency of nonsuicidal self-injury. This study adds to the growing evidence that sleep disturbance may predict suicidal behaviours. Clinicians should thus regularly assess for sleep disturbances when evaluating suicidal behaviours in high-risk adolescents. Further research and clinical trials should investigate whether sleep-based interventions may be efficacious in reducing the prevalence of suicidal behaviours.

摘要

新出现的研究已将睡眠障碍确定为预测自我伤害行为的一个重要风险因素。然而,这种关系的时间顺序,尤其是在临床青少年样本中,仍知之甚少。本研究利用一项临床队列研究的二次分析,考察了有冒险和自我伤害行为的临床青少年中睡眠障碍与自我伤害行为(即非自杀性自伤和自杀未遂)之间的关系。采用交叉滞后结构方程模型,以确定在一个专门治疗冒险和自我伤害行为的门诊接受治疗的青少年样本(n = 238,89.5%为女性)中,基线睡眠障碍和自我伤害行为在一年随访期内是否相互为预测因素。在控制年龄、性别和抑郁症状后,基线时更严重的睡眠障碍(p = 0.001)独立预测随访时更高的自杀未遂次数。当用非自杀性自伤频率对睡眠障碍进行建模时,未发现双向关系。本研究进一步证明了睡眠障碍可能预测自杀行为。因此,临床医生在评估高危青少年的自杀行为时,应定期评估睡眠障碍情况。进一步的研究和临床试验应调查基于睡眠的干预措施是否能有效降低自杀行为的发生率。

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