Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, Los Angeles, California, USA.
Human Development & Family Studies, The Pennsylvania State University, State College, Pennsylvania, USA.
Suicide Life Threat Behav. 2020 Dec;50(6):1189-1197. doi: 10.1111/sltb.12658. Epub 2020 Jul 24.
To elucidate processes contributing to continuing self-harm in youth at very high risk for suicide, focusing on sleep disturbance, a putative warning sign of imminent suicide risk.
101 youth (ages 12-18) selected for high risk of suicide/suicide attempts based on suicidal episodes plus repeated self-harm (suicide attempts and/or nonsuicidal self-injury [NSSI]). Youth were assessed at baseline, 6-, and 12-month follow-ups on measures of self-harm, suicidality, sleep, and depression.
Youth showed high rates of baseline sleep disturbance: 81.2% scored in the clinical range on the Pittsburgh Sleep Quality Index (PSQI); 81.2% reported an evening (night owl) circadian preference. PSQI score was associated with elevated levels of self-harm (suicide attempts and NSSI) contemporaneously and predicted future self-harm within 30 days. Rates of self-harm were high during follow-up: 45.0% and 33.7% at 6 and 12 months, respectively.
Results underscore the need to move beyond an acute treatment model to prevent recurrent and potentially deadly self-harm, the importance of clarifying mechanisms contributing to elevated suicide/self-harm risk, and the potential promise of engaging sleep as a therapeutic target for optimizing treatment and elucidating mechanistic processes.
阐明导致青少年自杀高风险人群持续自我伤害的过程,重点关注睡眠障碍,这是即将发生自杀风险的一个潜在警告信号。
根据自杀发作加上反复的自我伤害(自杀尝试和/或非自杀性自我伤害[NSSI]),选择 101 名自杀风险/自杀尝试高风险的青少年(年龄 12-18 岁)。在基线、6 个月和 12 个月的随访中,对自我伤害、自杀意念、睡眠和抑郁进行评估。
青少年的睡眠障碍率很高:81.2%的人在匹兹堡睡眠质量指数(PSQI)上得分处于临床范围;81.2%的人报告晚上(夜猫子)的昼夜节律偏好。PSQI 得分与同时发生的更高水平的自我伤害(自杀尝试和 NSSI)有关,并预测了 30 天内的未来自我伤害。随访期间的自我伤害率很高:分别为 6 个月和 12 个月时的 45.0%和 33.7%。
研究结果强调需要超越急性治疗模式,以预防反复发生且可能致命的自我伤害,需要阐明导致自杀/自我伤害风险升高的机制的重要性,以及将睡眠作为治疗目标以优化治疗和阐明机制过程的潜在前景。