Basharov M A, Vol'kenshteĭn M V, Golovanov I B, Nauchitel' V V, Sobolev V M
Mol Biol (Mosk). 1987 May-Jun;21(3):743-9.
The problem of stabilization of oligopeptide alpha-helix conformation is discussed. The stabilizing role of intramolecular H-bonds and coulombic interactions for single molecules was shown. The influence of media results in the competition for formation of inter and intramolecular H-bonds and for coulombic interactions. High competitive media, eg. water, diminishes alpha-helix stability.
讨论了寡肽α-螺旋构象的稳定问题。展示了分子内氢键和库仑相互作用对单个分子的稳定作用。介质的影响导致分子间和分子内氢键形成以及库仑相互作用的竞争。高竞争性介质,例如水,会降低α-螺旋的稳定性。