Dhar Sandipan, Srinivas Sahana M
Departments of Pediatric Dermatology, Institute of Child Health, Kolkata, West Bengal, India.
Department of Pediatric Dermatology, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India.
Indian J Dermatol. 2022 Jul-Aug;67(4):374-380. doi: 10.4103/ijd.ijd_570_22.
Psoriasis is a common, chronic, immune-mediated, multisystem, inflammatory disorder. It affects all age groups, including infancy. In one-third of the cases, the onset of the disease is in the first and second decades of life. Childhood psoriasis significantly affects the quality of life of the child as well as that of the entire family. Pediatric psoriasis has distinct clinical presentations and evolves with time. Like in adults, chronic plaque psoriasis has been found to be the most common type of childhood psoriasis. Psoriatic plaques in children are less pruritic, smaller and thinner with less prominent scaling. In pigmented skin, the erythema is less prominent and plaques appear violaceous or hyperpigmented. Pediatric psoriasis can be associated with arthritis, metabolic syndrome, depression and anxiety. Hence all children should be screened routinely for associated comorbidities. Management of pediatric psoriasis is challenging owing to the limitation of approved therapies. 'Proactive therapy' is a recent approach in childhood-onset psoriasis that would help to prevent the severity of flare-ups, thus improving the quality of life.
银屑病是一种常见的、慢性的、免疫介导的、多系统炎症性疾病。它影响所有年龄组,包括婴儿期。在三分之一的病例中,疾病发病于生命的第一个和第二个十年。儿童银屑病严重影响儿童以及整个家庭的生活质量。儿童银屑病有独特的临床表现,并随时间演变。与成人一样,慢性斑块状银屑病是儿童银屑病最常见的类型。儿童银屑病斑块瘙痒较轻,更小、更薄,鳞屑不那么明显。在有色人种皮肤中,红斑不那么明显,斑块呈紫色或色素沉着。儿童银屑病可与关节炎、代谢综合征、抑郁和焦虑相关。因此,所有儿童都应定期筛查相关合并症。由于获批疗法有限,儿童银屑病的管理具有挑战性。“积极治疗”是儿童期发病银屑病的一种新方法,有助于预防病情突然加重的严重程度,从而提高生活质量。