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股骨近端长钉与短钉治疗转子间骨折的假体周围骨折:一项为期10年的单中心队列研究

Periprosthetic Fractures in Long Versus Short Proximal Femoral Nailing for Intertrochanteric Fractures: A 10-Year Single-Centre Cohort Study.

作者信息

Nasim Omer, Kohli Suraj, Eskander Boulos, Girgis Sameh, Kent Michael

机构信息

Trauma and Orthopaedics, University Hospitals Dorset, Poole, GBR.

Trauma and Orthopaedics, Salisbury NHS Foundation Trust, Salisbury, GBR.

出版信息

Cureus. 2022 Dec 23;14(12):e32892. doi: 10.7759/cureus.32892. eCollection 2022 Dec.

Abstract

Background Neck of femur (NOF) fractures, including intertrochanteric fractures, are common fragility fractures seen in the elderly population and are often amenable to fixation with a proximal femoral nail (PFN). However, there is conflicting evidence regarding the incidence of peri-prosthetic fractures with each device. Several studies from the 1990s and a recent meta-analysis have shown a higher incidence of peri-prosthetic fractures in the short PFN cohort. Other studies have shown a lower reoperation rate with short PFNs, and no statistically significant differences have been quoted in the rates of peri-prosthetic fractures in systematic reviews. Aim The purpose of this retrospective study, therefore, was to assess the peri-prosthetic fracture rate and failure rates of elderly neck of femur (NOF) fractures implanted with either a short or long proximal femoral nail (PFN). Materials and methods A retrospective study was conducted in a single orthopaedic department (University Hospital Dorset, Poole, GBR) using collected data on all extracapsular neck of femur fracture patients from the national hip fracture database (NHFD) from January 1, 2011, to December 23, 2021. The data collected included patient age, sex, the American Society of Anesthesiologists (ASA) type of neck of femur fracture, type of surgery performed, any further peri-prosthetic fractures, and time to re-operation in that subset of the group. The implants used were the Stryker Gamma 3 Nail and the Smith Nephew (Trigen and Intertan). All patients were allowed to fully weight bear as tolerated and received both orthopaedic and elderly medical care. Failure was defined as a cut-out or implant fracture. Results From January 1, 2011, to December 23, 2021, there were 1010 extracapsular neck of femur fractures recorded on the National Hip Fracture Database (NHFD) treated with a PFN from the study centre. Of those patients, 11 had pathological fractures and were excluded. 649 patients had long PFNs, and 350 had short PFNs. Of the total of 999 patients, 254 (25%) were male and 745 (75%) were female. More than 80% of the patients in the sample were over the age of 75. The majority of patients in both groups had A1/A2 fractures (short 84.3%, long 49.1%). The rate of periprosthetic fractures in the short PFNs was 1.71%, and the failure rate was 0.57%. The rate of periprosthetic fractures in the long PFNs was 0.62%, with a failure rate of 0.92%. The multi-nominal logistic regression model did not show statistically significant odds ratios (OR) for the following variables: long/short nails, male/female gender, age, ASA, or type of fracture. The female gender was associated with a higher risk of both periprosthetic fractures and failures (OR of 2.232 and 2.95), but this was not found to be statistically significant. Similarly, unstable A3 fractures had a much higher risk of failure (OR of 2.691) compared to periprosthetic fractures (OR of 0.985). However, this was not statistically significant. Conclusion Overall, this study has identified that in a patient population that is predominantly female and over the age of 75, the risk of periprosthetic fracture rate and the failure rate is similar in both the use of a short or a long PFN for intertrochanteric fractures.

摘要

背景

股骨颈(NOF)骨折,包括粗隆间骨折,是老年人群中常见的脆性骨折,通常可用股骨近端髓内钉(PFN)进行固定。然而,关于每种器械周围假体骨折的发生率,证据存在冲突。20世纪90年代的几项研究和最近的一项荟萃分析表明,短PFN组的周围假体骨折发生率较高。其他研究表明,短PFN的再次手术率较低,系统评价中未提及周围假体骨折发生率的统计学显著差异。目的:因此,本回顾性研究的目的是评估植入短或长股骨近端髓内钉(PFN)的老年股骨颈(NOF)骨折的周围假体骨折率和失败率。材料和方法:在一个骨科科室(英国普尔多塞特大学医院)进行了一项回顾性研究,使用了从国家髋部骨折数据库(NHFD)收集的2011年1月1日至2021年12月23日期间所有股骨颈囊外骨折患者的数据。收集的数据包括患者年龄、性别、美国麻醉医师协会(ASA)股骨颈骨折类型、所进行的手术类型、任何进一步的周围假体骨折以及该组子集中再次手术的时间。使用的植入物是史赛克Gamma 3髓内钉和史密斯&奈普(Trigen和Intertan)。所有患者在耐受的情况下允许完全负重,并接受骨科和老年医学护理。失败定义为内植物切出或骨折。结果:2011年1月1日至2021年12月23日,国家髋部骨折数据库(NHFD)记录了研究中心用PFN治疗的1010例股骨颈囊外骨折。其中11例为病理性骨折,被排除。649例患者使用长PFN,350例患者使用短PFN。在总共999例患者中,254例(25%)为男性,745例(75%)为女性。样本中超过80%的患者年龄超过75岁。两组中的大多数患者为A1/A2骨折(短PFN组为84.3%,长PFN组为49.1%)。短PFN组的周围假体骨折率为1.71%,失败率为0.57%。长PFN组的周围假体骨折率为0.62%,失败率为0.92%。多项逻辑回归模型未显示以下变量的统计学显著优势比(OR):长/短髓内钉、男性/女性性别、年龄、ASA或骨折类型。女性性别与周围假体骨折和失败的风险较高相关(OR分别为2.232和2.95),但未发现具有统计学显著性。同样,与周围假体骨折(OR为0.985)相比,不稳定的A3骨折失败风险高得多(OR为2.691)。然而,这也没有统计学显著性。结论:总体而言,本研究发现,在以女性为主且年龄超过75岁的患者群体中,对于粗隆间骨折,使用短或长PFN时周围假体骨折率和失败率相似。

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