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股骨转子间骨折和转子下骨折应采用短髓内钉还是长髓内钉治疗?一项多中心队列研究。

Should Pertrochanteric and Subtrochanteric Fractures Be Treated with a Short or Long Intramedullary Nail?: A Multicenter Cohort Study.

作者信息

Viberg Bjarke, Eriksen Lasse, Højsager Katia D, Højsager Frederik D, Lauritsen Jens, Palm Henrik, Overgaard Søren

机构信息

Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark.

Department of Orthopaedic Surgery and Traumatology, Hospital Lillebaelt, University Hospital of Southern Denmark, Kolding, Denmark.

出版信息

J Bone Joint Surg Am. 2021 Dec 15;103(24):2291-2298. doi: 10.2106/JBJS.20.01904.

Abstract

BACKGROUND

The purpose of the present multicenter cohort study was to compare the rates of reoperation in elderly patients with pertrochanteric and subtrochanteric fractures that had been treated with a short or long intramedullary nail.

METHODS

Eleven orthopaedic departments across Denmark delivered data that had been obtained from the Danish Multidisciplinary Hip Fracture Registry (DMHFR) and a review of health-care records. With use of surgical procedure codes for pertrochanteric and subtrochanteric fractures that had been treated with an intramedullary nail, the DMRHF was searched to identify patients who had been ≥65 years of age between 2008 and 2013. The health-care records for patients who had had major reoperations, defined as any reoperation with the exclusion of simple hardware removal, were retrieved from the DMHFR, were reviewed for the type of intramedullary nail and missed reoperations, including peri-implant fractures, within 2 years of follow-up. Crude logistic regression analysis with adjustment for age, sex, and comorbidity was performed, yielding odds ratios (ORs) with 95% confidence intervals (CIs).

RESULTS

Of 2,245 pertrochanteric fractures, 1,867 were treated with a short intramedullary nail and 378 were treated with a long intramedullary nail. The rate of major reoperations was 4.0% in the short intramedullary nail group and 6.3% in the long intramedullary nail group. This yielded a crude OR of 1.61 (1.01 to 2.60) and an adjusted OR of 1.67 (1.04 to 2.70). Of 909 subtrochanteric fractures, 308 were treated with a short intramedullary nail and 601 were treated with a long intramedullary nail. The rate of major reoperations was 8.4% in the short intramedullary nail group and 4.0% in the long intramedullary nail group, yielding a crude OR of 0.45 (0.25 to 0.80) and an adjusted OR of 0.45 (0.25 to 0.81).

CONCLUSIONS

This is the first study confirming the theory that, for subtrochanteric fractures, a long intramedullary nail has a lower rate of major reoperations compared with a short intramedullary nail. In contrast, a short intramedullary nail has a lower rate of major reoperations compared with a long intramedullary nail for pertrochanteric fractures but with a lower absolute risk reduction compared with the results for subtrochanteric intramedullary nailing. There is a need for validation of these results in other large studies, especially for pertrochanteric fractures.

LEVEL OF EVIDENCE

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

本多中心队列研究的目的是比较接受短髓内钉或长髓内钉治疗的老年转子间骨折和转子下骨折患者的再次手术率。

方法

丹麦的11个骨科科室提供了从丹麦多学科髋部骨折登记处(DMHFR)获取的数据以及对医疗记录的回顾。利用髓内钉治疗转子间骨折和转子下骨折的手术操作编码,在DMRHF中搜索2008年至2013年间年龄≥65岁的患者。从DMHFR中检索接受重大再次手术(定义为排除单纯取出内固定物的任何再次手术)患者的医疗记录,审查髓内钉类型和随访2年内漏诊的再次手术情况,包括植入物周围骨折。进行了调整年龄、性别和合并症的粗逻辑回归分析,得出比值比(OR)及95%置信区间(CI)。

结果

在2245例转子间骨折中,1867例接受短髓内钉治疗,378例接受长髓内钉治疗。短髓内钉组的重大再次手术率为4.0%,长髓内钉组为6.3%。这得出粗OR为1.61(1.01至2.60),调整后OR为1.67(1.04至2.70)。在909例转子下骨折中,308例接受短髓内钉治疗,601例接受长髓内钉治疗。短髓内钉组的重大再次手术率为8.4%,长髓内钉组为4.0%,粗OR为0.45(0.25至0.80),调整后OR为0.45(0.25至0.81)。

结论

这是第一项证实以下理论的研究:对于转子下骨折,与短髓内钉相比,长髓内钉的重大再次手术率更低。相比之下,对于转子间骨折,短髓内钉的重大再次手术率低于长髓内钉,但与转子下髓内钉固定的结果相比,绝对风险降低幅度较小。需要在其他大型研究中验证这些结果,尤其是对于转子间骨折。

证据水平

治疗性III级。有关证据水平的完整描述,请参阅作者须知。

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