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Randomized Trials Fit for the 21st Century. A Joint Opinion from the European Society of Cardiology, American Heart Association, American College of Cardiology, and the World Heart Federation.

作者信息

Bowman Louise, Weidinger Franz, Albert Michelle A, Fry Edward T A, Pinto Fausto J

机构信息

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

出版信息

Glob Heart. 2022 Dec 16;17(1):85. doi: 10.5334/gh.1178. eCollection 2022.

DOI:10.5334/gh.1178
PMID:36578917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9756910/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80f0/9756910/7e07617b3579/gh-17-1-1178-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80f0/9756910/7e07617b3579/gh-17-1-1178-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80f0/9756910/7e07617b3579/gh-17-1-1178-g1.jpg

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本文引用的文献

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Poor trials of health steps are worse than none, scientists say.
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Trends in COVID-19 therapeutic clinical trials.COVID-19治疗性临床试验的趋势。
Nat Rev Drug Discov. 2021 Apr;20(4):254-255. doi: 10.1038/d41573-021-00037-3.
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Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.用于治疗新冠肺炎的抗病毒药物 repurposed - 世界卫生组织团结试验中期结果
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Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.204 个国家和地区 1990-2019 年 369 种疾病和伤害导致的全球负担:2019 年全球疾病负担研究的系统分析。
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Real World Data as Trial End Points: Off and Running With a Long Way to Go.
Circulation. 2020 Jul 21;142(3):214-216. doi: 10.1161/CIRCULATIONAHA.120.048019. Epub 2020 Jul 20.
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Dexamethasone in Hospitalized Patients with Covid-19.地塞米松在 COVID-19 住院患者中的应用。
N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17.
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Understanding the use of observational and randomized data in cardiovascular medicine.了解心血管医学中观察性数据和随机数据的使用。
Eur Heart J. 2020 Jul 14;41(27):2571-2578. doi: 10.1093/eurheartj/ehaa020.
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EuroHeart: European Unified Registries On Heart Care Evaluation and Randomized Trials.欧洲心脏计划:欧洲心脏护理评估与随机试验统一注册库。
Eur Heart J. 2019 Sep 1;40(33):2745-2749. doi: 10.1093/eurheartj/ehz599.
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Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.依洛尤单抗与急性冠脉综合征后的心血管结局。
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