Jin Byung Chul, Ahn Ae Ri, Kim Seong-Hun, Seo Seung Young
Department of Internal Medicine, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju 54907, South Korea.
Department of Pathology, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University, Biomedical Research Institute of Jeonbuk National University Hospital, and Research Institute for Endocrine Sciences, Jeonju 56445, South Korea.
World J Clin Cases. 2022 Dec 6;10(34):12793-12798. doi: 10.12998/wjcc.v10.i34.12793.
Endoscopic submucosal dissection (ESD) is the treatment of choice for early gastric cancer and premalignant gastric dysplasia. In some cases, ESD induced ulcer heals as a polypoid nodular scar (PNS). These scars may make the physicians raise several clinical implications such as post-ESD neoplastic recurrence.
We described a case of gastric ESD induced PNS which is regressed after eradication. A 58-year-old male patient was referred to the outpatient clinic for evaluation and treatment of gastric low-grade dysplasia (LGD). ESD was performed. A PNS was developed at the ESD site. An endoscopic biopsy was done and there was no histological evidence of remnant tumor or recurrence but a hyperplastic mucosal change. The PNS showed increase in size in follow-up endoscopy, and the biopsy specimen demonstrated infestation. eradication was done and the PNS was regressed.
eradication is considerable for the regression of PNS if infestation is confirmed.
内镜下黏膜剥离术(ESD)是早期胃癌和癌前胃发育异常的首选治疗方法。在某些情况下,ESD引起的溃疡愈合为息肉样结节性瘢痕(PNS)。这些瘢痕可能会使医生产生一些临床疑虑,如ESD后肿瘤复发。
我们描述了一例胃ESD引起的PNS在根除后消退的病例。一名58岁男性患者因胃低度发育异常(LGD)前来门诊评估和治疗。进行了ESD。ESD部位出现了PNS。进行了内镜活检,没有残余肿瘤或复发的组织学证据,但有增生性黏膜改变。在随访内镜检查中,PNS大小增加,活检标本显示有感染。进行了根除治疗,PNS消退。
如果确认有感染,根除治疗对于PNS的消退是值得考虑的。