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改变交通轨道式关节牵开器的方向如何影响伴阻塞性睡眠呼吸暂停的颞下颌关节强直患者手术的结果?

How does changing the vector of transport disc distraction affect the outcomes of surgery in patients of temporomandibular joint ankylosis with obstructive sleep apnea?

机构信息

Department of Oral & Maxillofacial Surgery, All India Institute of Medical Sciences, New Delhi, India.

Department of Anaesthesia, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Oral Maxillofac Surg. 2024 Mar;28(1):235-244. doi: 10.1007/s10006-022-01133-3. Epub 2022 Dec 29.

Abstract

PURPOSE

Temporomandibular joint ankylosis (TMJA) in children is associated with retrognathia, reduction in pharyngeal airway volume (PAV), and obstructive sleep apnea (OSA). Distraction-osteogenesis (DO) is the proven method in the management of OSA. There is paucity in literature about the effect of distraction vector on PAV. It can be expected that an oblique vector would improve PAV and relieve OSA. Thus, the study was designed to explore the feasibility, advantages, and disadvantages of this modified technique for managing TMJA and OSA simultaneously.

MATERIALS AND METHOD

The investigators designed a prospective study on patients of TMJA with retrognathia. Ethical approval was obtained (IECPG-547/14.11.2018). In all patients, simultaneous ankylosis release and mandibular distraction were performed. Primary outcome variables were improvement in 3-dimensional (3D) PAV and maximal interincisal opening (MIO). Secondary outcome variables were changed mandibular length, distraction relapse, and re-ankylosis. Paired t-test and multivariate ANOVA were used to assess all the parameters.

RESULT

The study included 13 joints in 8 patients of TMJA with retrognathia (2 unilateral and 6 bilateral ankylosis) with mean age of 14.25 ± 7.37 years. Mean distraction performed was 19 ± 4.0 mm. There was a statistically significant improvement of PAV by 225% (p = 0.002), a reduction in Epworth's scale (p = 0.017), an increase in MIO (p = 0.001), and an increase in mandibular length. Three patients had re-ankylosis at the 25-month follow-up.

CONCLUSION

The results of the present study conclude that modification of distraction vector improves 3D PAV and MIO in TMJA patients, with the added advantage of a reduction in overall treatment time and improved patient compliance.

摘要

目的

儿童颞下颌关节强直(TMJA)与小下颌、咽腔气道容积(PAV)减少和阻塞性睡眠呼吸暂停(OSA)有关。牵引成骨术(DO)是治疗 OSA 的有效方法。关于牵引矢量对 PAV 的影响,文献记载较少。可以预期,斜行矢量会改善 PAV 并缓解 OSA。因此,本研究旨在探讨同时治疗 TMJA 和 OSA 的改良技术的可行性、优点和缺点。

材料和方法

研究人员设计了一项关于小下颌 TMJA 患者的前瞻性研究。获得了伦理批准(IECPG-547/14.11.2018)。在所有患者中,同时进行了关节强直松解和下颌骨牵引。主要结局变量是 3 维(3D)PAV 和最大切牙开口(MIO)的改善。次要结局变量是下颌骨长度变化、牵引复发和再强直。采用配对 t 检验和多变量方差分析评估所有参数。

结果

该研究纳入了 8 例 TMJA 伴小下颌的 13 个关节(2 例单侧,6 例双侧强直),平均年龄为 14.25±7.37 岁。平均牵引距离为 19±4.0mm。PAV 显著改善 225%(p=0.002),Epworth 量表评分降低(p=0.017),MIO 增加(p=0.001),下颌骨长度增加。3 例患者在 25 个月随访时出现再强直。

结论

本研究结果表明,改变牵引矢量可改善 TMJA 患者的 3D PAV 和 MIO,且具有缩短总治疗时间和提高患者依从性的额外优势。

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