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高社会风险对农村社区居住的老年人大心血管健康状况的有害影响。一项基于人群的、纵向前瞻性研究。

Detrimental effect of high social risk on the cardiovascular health status of community-dwelling older adults living in rural settings. A population-based, longitudinal prospective study.

机构信息

School of Medicine and Research Center, Universidad Espíritu Santo - Ecuador, Samborondón, Ecuador.

Biostatistics/Epidemiology, Freenome, Inc., South San Francisco, CA, USA.

出版信息

Int J Cardiol. 2023 Mar 15;375:124-130. doi: 10.1016/j.ijcard.2022.12.044. Epub 2022 Dec 26.

DOI:10.1016/j.ijcard.2022.12.044
PMID:36581111
Abstract

BACKGROUND

Information of the effect of social risk on the cardiovascular health (CVH) status among individuals living in rural settings is limited. We aim to assess this effect in participants of the Three Villages Study cohort.

METHODS

Following a longitudinal prospective design, older adults living in rural Ecuador received baseline social risk determinations by means of social determinants of health components included in the Gijon's Social-Familial Evaluation Scale (SFES) together with clinical interviews and procedures to determine CVH status included in the Life's Simple 7 construct. Those who also received CVH assessment at the end of the study were included. Random-effects generalized least square and mixed logistic regression models were fitted to assess the longitudinal effect of social risk on CVH metrics, after adjusting for relevant covariates.

RESULTS

The study included 443 community dwellers (mean age: 67 ± 7 years). The Gijon's SFES mean score was 9.8 ± 2.7 points. The mean number of ideal CVH metrics at baseline was 3.1 ± 1.3, which decreased to 2.6 ± 1.2 (β: -0.467; 95% C.I.: -0.588 to -0.346), after a mean of 7.31 ± 3.26 years of follow-up. The total Gijon's SFES score was higher among individuals with a worsening CVH status compared to those who did not (10.4 ± 2.6 versus 9.3 ± 2.6; p < 0.001). The ideal CVH status declined 1.23 (95% C.I.: 1.13-1.34) times per point of change in the total Gijon's SFES score.

CONCLUSION

Study results indicate a deleterious effect of high social risk on CVH status at follow-up in this underserved population.

摘要

背景

关于社会风险对农村环境中个体心血管健康(CVH)状况影响的信息有限。我们旨在评估三村研究队列参与者的这种影响。

方法

采用纵向前瞻性设计,厄瓜多尔农村地区的老年人通过健康决定因素包括在吉洪社会-家庭评估量表(SFES)中的社会决定因素,以及临床访谈和确定 CVH 状态的程序来确定社会风险状况,包括生活的 7 个简单要素。那些在研究结束时也接受 CVH 评估的人被纳入研究。在调整了相关协变量后,采用随机效应广义最小二乘法和混合逻辑回归模型来评估社会风险对 CVH 指标的纵向影响。

结果

该研究纳入了 443 名社区居民(平均年龄:67±7 岁)。Gijon 的 SFES 平均得分为 9.8±2.7 分。基线时理想 CVH 指标的平均数量为 3.1±1.3,经过平均 7.31±3.26 年的随访后降至 2.6±1.2(β:-0.467;95%CI:-0.588 至-0.346)。与 CVH 状况未恶化的个体相比,总吉洪 SFES 评分较高的个体 CVH 状态恶化(10.4±2.6 与 9.3±2.6;p<0.001)。总吉洪 SFES 评分每变化 1 分,理想 CVH 状态下降 1.23(95%CI:1.13-1.34)倍。

结论

研究结果表明,在这个服务不足的人群中,高社会风险对随访时的 CVH 状态有不良影响。

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