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改良“补充三明治”技术治疗角膜穿孔:1例病例报告及文献综述

Modified "Top-up sandwich" technique for the management of corneal perforations: A case report and a literature review.

作者信息

Elhaddad Omar, Achiron Asaf, Yahalomi Tal, Avadhanam Venkata, Tole Derek, Darcy Kieran

机构信息

Bristol Eye Hospital, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom.

Faculty of Medicine, Alexandria University, Egypt.

出版信息

Am J Ophthalmol Case Rep. 2022 Dec 14;29:101765. doi: 10.1016/j.ajoc.2022.101765. eCollection 2023 Mar.

Abstract

PURPOSE

We describe a modified technique for managing a peripheral, non-infected, corneal perforation using a "Sandwich" technique that combines posterior lamellar keratoplasty, an amniotic membrane patch and a Gundersen conjunctival flap.

OBSERVATIONS

A 75-year-old female patient presented with Sjogren's syndrome-related corneal perforation. A mini-Descemet stripping automated endothelial keratoplasty (DSAEK) graft (5 mm) was introduced into the anterior chamber and was mobilized to plug the perforation. Then, two amniotic membrane patches were stacked over the perforation and glued. Finally, the whole area was covered with a Gundersen conjunctival flap, mobilized from the inferior conjunctiva and secured in place using interrupted 10-0 nylon sutures. A step-by-step guide is also described. At three months, the final visual acuity was 6/9. A literature review revealed ten cases in which a posterior lamellar graft was effectively employed to treat corneal perforations.

CONCLUSIONS AND IMPORTANCE

We described a modified approach for treating peripheral corneal perforation surgically. This "sandwich" approach is simple to replicate and can give quick healing with few visual repercussions. Our detailed guide may be utilized to obtain similar results and may be added to the array of treatment options for peripheral corneal perforation.

摘要

目的

我们描述一种改良技术,使用“三明治”技术处理周边非感染性角膜穿孔,该技术结合了后板层角膜移植术、羊膜贴片和冈德森结膜瓣。

观察结果

一名75岁女性患者因干燥综合征相关角膜穿孔前来就诊。将一片小型深板层内皮角膜移植术(DSAEK)移植物(5毫米)植入前房并移动至穿孔处进行封堵。然后,在穿孔处堆叠两片羊膜贴片并粘贴。最后,用从下方结膜取下的冈德森结膜瓣覆盖整个区域,并用10-0尼龙间断缝线固定在位。文中还描述了详细步骤指南。三个月时,最终视力为6/9。文献回顾显示有十例使用后板层移植物有效治疗角膜穿孔的病例。

结论与意义

我们描述了一种手术治疗周边角膜穿孔的改良方法。这种“三明治”方法易于复制,能实现快速愈合且对视力影响较小。我们的详细指南可用于获得类似结果,并可补充到周边角膜穿孔的治疗方案中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866f/9792391/3dab9b5d9b2f/gr1a.jpg

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