Banodkar Akshaya Bhupesh, Nandgaonkar Vaibhavi Pandurang, Gaikwad Rajesh Prabhakar, Fernandes Lynette Custodio, Patil Chitra Laxmikant, Batho Amrita Dharmendra
Department of Periodontology, Government Dental College and Hospital, St. George Hospital Campus, Mumbai, Maharashtra, India.
J Indian Soc Periodontol. 2022 Nov-Dec;26(6):539-543. doi: 10.4103/jisp.jisp_453_21. Epub 2022 Nov 14.
Surgical site infection (SSI) is one of the common postoperative complications observed after various periodontal surgeries, and sutures play a vital role in its causation. Thus, the aim of this study is to evaluate and compare the efficacy of a novel tetracycline-coated suture with triclosan-coated and nonantibacterial-coated sutures on bacterial load reduction to prevent SSI by measuring the zone of inhibition.
Twenty systemically healthy individuals with moderate chronic periodontitis were included in this study. Fresh unstimulated saliva was collected from each patient and inoculated on three different blood agar plates. Sutures were divided into three groups (Group A: Tetracycline-coated suture, Group B: Triclosan-coated suture, Group C [control group]: Nonantibacterial-coated suture). The antibacterial efficacy of each suture was evaluated by performing agar diffusion test. The zone of inhibition around each suture was calculated, and statistical analysis was performed for the same using Kruskall-Wallis ANOVA test and Mann-Whitney U-test.
On intergroup comparison, there was a statistically highly significant difference seen for the zone of inhibition between the groups ( < 0.01) with the highest values in Group A (14.45 mm), followed by Group B (1.4 mm) and least in Group C (0 mm).
Tetracycline-coated suture is more efficacious than triclosan-coated suture to reduce bacterial load and further prevent SSIs. However, clinical trial is must to prove the same.
手术部位感染（SSI）是各类牙周手术后常见的术后并发症之一，缝线在其发生过程中起着至关重要的作用。因此，本研究的目的是通过测量抑菌圈，评估并比较新型四环素涂层缝线与三氯生涂层缝线及非抗菌涂层缝线在减少细菌负荷以预防手术部位感染方面的效果。
本研究纳入了20名患有中度慢性牙周炎的全身健康个体。从每位患者收集新鲜的非刺激性唾液，并接种在三个不同的血琼脂平板上。缝线分为三组（A组：四环素涂层缝线；B组：三氯生涂层缝线；C组[对照组]：非抗菌涂层缝线）。通过琼脂扩散试验评估每种缝线的抗菌效果。计算每条缝线周围的抑菌圈，并使用Kruskal-Wallis方差分析检验和Mann-Whitney U检验进行统计分析。
组间比较时，各组之间抑菌圈存在统计学上的高度显著差异（<0.01），A组（14.45毫米）的值最高，其次是B组（1.4毫米），C组最低（0毫米）。
四环素涂层缝线在减少细菌负荷及进一步预防手术部位感染方面比三氯生涂层缝线更有效。然而，必须通过临床试验来证实这一点。
