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一名患有严重再生障碍性贫血的孕妇并发子痫前期:病例报告

Preeclampsia in a pregnant woman with severe aplastic anemia: A case report.

作者信息

Kawabata Ikuno, Yokote Ryoko, Kasano Sayuri, Ogawa Jun, Kato Masahiko, Ichikawa Tomoko, Yonezawa Mirei, Kuwabara Yoshimitsu, Yamaguchi Hiroki, Suzuki Shunji

机构信息

Department of Obstetrics and Gynecology Nippon Medical School Tokyo Japan.

Department of Hematology Nippon Medical School Tokyo Japan.

出版信息

Clin Case Rep. 2022 Dec 26;10(12):e6789. doi: 10.1002/ccr3.6789. eCollection 2022 Dec.

DOI:10.1002/ccr3.6789
PMID:36583203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9792651/
Abstract

A pregnant woman with severe aplastic anemia was managed using biweekly red blood cell transfusion and oral eltrombopag olamine administration during pregnancy. She was diagnosed with preeclampsia at 35 weeks of gestation. The severity of aplastic anemia is very important for predicting the course of pregnancy.

摘要

一名患有严重再生障碍性贫血的孕妇在孕期接受了每两周一次的红细胞输注和口服艾曲泊帕乙醇胺治疗。她在妊娠35周时被诊断为先兆子痫。再生障碍性贫血的严重程度对于预测妊娠过程非常重要。

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本文引用的文献

1
Use of Thrombopoietin Receptor Agonists in Pregnancy: A Review of the Literature.血小板生成素受体激动剂在妊娠中的应用:文献综述
Hematol Oncol Stem Cell Ther. 2022 Mar 1;15(1):1-6. doi: 10.1016/j.hemonc.2021.05.004.
2
Maternal and Perinatal Morbidity and Mortality Associated With Anemia in Pregnancy.妊娠相关贫血与孕产妇及围生儿发病率和死亡率的关系。
Obstet Gynecol. 2019 Dec;134(6):1234-1244. doi: 10.1097/AOG.0000000000003557.
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Long-term outcome of pregnancy complicating with severe aplastic anemia under supportive care.支持治疗下妊娠合并严重再生障碍性贫血的长期结局
Taiwan J Obstet Gynecol. 2017 Oct;56(5):632-635. doi: 10.1016/j.tjog.2017.08.010.
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Mild anemia during pregnancy upregulates placental vascularity development.孕期轻度贫血会上调胎盘血管生成。
Med Hypotheses. 2017 May;102:37-40. doi: 10.1016/j.mehy.2017.03.007. Epub 2017 Mar 6.
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Maternal hemoglobin concentration and hematocrit values may affect fetus development by influencing placental angiogenesis.母体血红蛋白浓度和血细胞比容值可能通过影响胎盘血管生成来影响胎儿发育。
J Matern Fetal Neonatal Med. 2017 Jan;30(2):199-204. doi: 10.3109/14767058.2016.1168395. Epub 2016 Apr 14.
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Guidelines for the diagnosis and management of adult aplastic anaemia.成人再生障碍性贫血诊断与治疗指南。
Br J Haematol. 2016 Jan;172(2):187-207. doi: 10.1111/bjh.13853. Epub 2015 Nov 16.
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Aplastic anemia associated with pregnancy: maternal and fetal complications.妊娠相关性再生障碍性贫血:母婴并发症
J Matern Fetal Neonatal Med. 2016;29(7):1120-4. doi: 10.3109/14767058.2015.1037733. Epub 2015 Sep 15.
8
Role of vascular endothelial growth factor and placental growth factor expression on placenta structure in pre-eclamptic pregnancy.血管内皮生长因子和胎盘生长因子表达在子痫前期妊娠胎盘结构中的作用
J Obstet Gynaecol Res. 2015 Oct;41(10):1533-40. doi: 10.1111/jog.12751. Epub 2015 Jul 14.
9
Pregnancy and myelodysplastic syndrome: an analysis of the clinical characteristics, maternal and fetal outcomes.妊娠与骨髓增生异常综合征:临床特征、母婴结局分析
J Matern Fetal Neonatal Med. 2015;28(18):2155-9. doi: 10.3109/14767058.2014.980229. Epub 2014 Nov 14.
10
Association of severe thrombocytopenia and poor prognosis in pregnancies with aplastic anemia.再生障碍性贫血妊娠中严重血小板减少与不良预后的关联。
PLoS One. 2014 Jul 24;9(7):e103066. doi: 10.1371/journal.pone.0103066. eCollection 2014.