Glover A T, Grove A S
Ophthalmology Service, Brooke Army Medical Center, Fort Sam, Houston, TX 78234-6200.
Ophthalmology. 1987 Aug;94(8):1008-12. doi: 10.1016/s0161-6420(87)33352-4.
A 13-year-old boy presented with a 2-month history of swelling of the right upper eyelid and displacement of the right eye. Computed tomography (CT) showed a tumor in the right orbit and a large osteolytic defect of the orbital frontal bone. At surgery a yellowish-tan mass was found replacing the orbital roof and abutting the dura. Incisional biopsy established the diagnosis of eosinophilic granuloma. In the absence of further therapy, the mass resolved, and the bony defect completely reossified within 14 months. During more than 2 years of follow-up, there has been no evidence of local recurrence or systemic disease. This case demonstrates that eosinophilic granuloma may resolve spontaneously with healing of bony defects, thus eliminating the need for adjunctive resection or radiation therapy in selected patients.
一名13岁男孩出现右上眼睑肿胀和右眼移位2个月的病史。计算机断层扫描（CT）显示右眼眶有一个肿瘤，眶额骨有一个大的骨质溶解缺损。手术中发现一个黄褐色肿块取代了眶顶并毗邻硬脑膜。切开活检确诊为嗜酸性肉芽肿。在未进行进一步治疗的情况下，肿块消退，骨缺损在14个月内完全重新骨化。在超过2年的随访中，没有局部复发或全身性疾病的证据。该病例表明，嗜酸性肉芽肿可能会随着骨缺损的愈合而自发消退，从而消除了部分患者辅助性切除或放射治疗的必要性。
