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先天性巨尿道症的产前诊断:病例报告及文献复习

Prenatal diagnosis of congenital megalourethra: case report and literature review.

作者信息

Öztürk Filiz Halıcı, Türkmen Gülenay Gençosmanoğlu, Ergun Elif, Tiryaki H Tuğrul, Şahin Dilek

机构信息

Department of Obstetrics and Gynecology, Ankara City Hospital, Ankara, Türkiye.

Department of Obstetrics and Gynecology, Dr. Sami Ulus Women and Child Health Training and Research Hospital, Ankara, Türkiye.

出版信息

Turk J Pediatr. 2022;64(6):1136-1145. doi: 10.24953/turkjped.2021.1252.

Abstract

BACKGROUND

Congenital megalourethra is an uncommon cause of lower urinary tract obstruction that is rarely prenatally diagnosed in second trimester sonographic examination as a cystic genital mass.

CASE

In the presented case, the megalourethra was accompanied with bilateral mild pelviectasis. The newborn had no morbidity during follow-up period. To review the literature, electronic databases including PubMed, Web of Science and Google Scholar were searched up to February 15, 2021. In 51 prenatally diagnosed cases in the literature, most of the cases had accompanying congenital anomalies, especially structural abnormalities in the genitourinary.

CONCLUSIONS

In the absence of associated abnormalities, the condition of the upper urinary tract is the main determinant of postnatal outcome. The outcome of congenital megalourethra may be good as in our case, but there may also be serious disorders such as renal failure, pulmonary hypoplasia, erectile dysfunction and fertility issues.

摘要

背景

先天性巨尿道是下尿路梗阻的罕见原因,在孕中期超声检查中很少作为囊性生殖器肿块进行产前诊断。

病例

在本病例中,巨尿道伴有双侧轻度肾盂积水。新生儿在随访期间无发病情况。为回顾文献,检索了截至2021年2月15日的电子数据库,包括PubMed、科学网和谷歌学术。在文献中51例产前诊断的病例中,大多数病例伴有先天性异常,尤其是泌尿生殖系统的结构异常。

结论

在无相关异常的情况下,上尿路状况是产后结局的主要决定因素。先天性巨尿道的结局可能如我们的病例一样良好,但也可能出现诸如肾衰竭、肺发育不全、勃起功能障碍和生育问题等严重疾病。

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