Department of Radiation Medicine, Oregon Health and Science University, Portland, Oregon, USA.
J Appl Clin Med Phys. 2023 Jan;24(1):e13877. doi: 10.1002/acm2.13877. Epub 2022 Dec 31.
To investigate the necessity of extending the output factor table (OF Table) of the Varian Eclipse Treatment Planning System for small field stereotactic radiosurgery (SRS) and stereotactic body radiosurgery (SBRT) treatments.
A new AcurosXB 15.6 beam model was created in the Eclipse Beam Configuration, which is identical to the one that has been used in the clinic with a default 3 × 3 cm to 40 × 40 cm OF Table, except the OF Table in the new model was extended to cover the range from 1 × 1 cm to 40 × 40 cm. 80 small square and rectangular output factors were measured on a Varian TrueBeam utilizing a Standard Imaging Exradin W2-1×1 scintillator detector, inside a PTW BeamScan water tank with 95 cm SSD at 5 cm depth. Cerenkov contamination was corrected using a rectangular field method (2 cm × 15 cm field). Nine Radiosurgery plans with primary jaw setting ranging from 0.7 cm to 2.0 cm were evaluated by both beam models. The monitor unit (MU) differences between the two beam models were calculated for identical 3-dimensional (3D) absolute dose distributions. Output factors, measured versus Eclipse calculated, were compared down to 0.5 × 0.5 cm primary jaw setting.
For the 6FFF beam, the difference between the two beam models was ∼ 6% for 1 × 1 cm jaw settings and 4% at 1.5 × 1.5 cm, with the extended OF Table requiring higher MUs for the same dose prescription and same 3-dimensional isodose distribution. For the 6MV beam, the corresponding difference is ∼7.5% for 1 × 1 cm, 5% for 1.5 × 1.5 cm, and 3% for 2 × 2 cm jaw settings, with the extended OF Table requiring higher MUs. For jaw settings smaller than 1 × 1 cm, measured dose can be considerably smaller than Eclipse predicted dose, even with the OF Table extension. This is reflected by the fact that the output factor for 0.5 × 0.5 cm, calculated via Eclipse external beam, was more than 30% greater than that measured for both 6FFF and 6MV beams.
Eclipse does a satisfactory job for primary jaw sizes down to 2 cm. For jaw settings smaller than 1.5 cm, the OF Table in Eclipse should be extended to improve the dose calculation accuracy.
研究为小适形立体定向放射外科(SRS)和立体定向体部放射治疗(SBRT)治疗扩展瓦里安 Eclipse 治疗计划系统的输出因子表(OF 表)的必要性。
在 Eclipse 束配置中创建了一个新的 AcurosXB 15.6 束模型,与已在临床中使用的模型相同,默认的 OF 表为 3×3cm 至 40×40cm,除了新模型中的 OF 表扩展到覆盖 1×1cm 至 40×40cm 的范围。在 95cm SSD 深度为 5cm 的 PTW BeamScan 水箱中,使用标准成像 Exradin W2-1×1 闪烁体探测器,在瓦里安 TrueBeam 上测量了 80 个小正方形和矩形输出因子。使用矩形场方法(2cm×15cm 场)校正了切伦科夫污染。评估了两个光束模型的 9 个放射外科计划,主准直器设置范围从 0.7cm 到 2.0cm。对于相同的三维(3D)绝对剂量分布,计算了两个光束模型之间的监测器单位(MU)差异。将测量值与 Eclipse 计算值进行比较,直到主准直器设置为 0.5×0.5cm。
对于 6FFF 束,两个光束模型之间的差异在 1×1cm 准直器设置时约为 6%,在 1.5×1.5cm 时为 4%,扩展的 OF 表要求在相同的剂量处方和相同的 3D 等剂量分布下使用更高的 MU。对于 6MV 束,相应的差异在 1×1cm 时约为 7.5%,在 1.5×1.5cm 时为 5%,在 2×2cm 准直器设置时为 3%,扩展的 OF 表要求使用更高的 MU。对于小于 1×1cm 的准直器设置,测量剂量可能明显小于 Eclipse 预测剂量,即使使用 OF 表扩展也是如此。这反映了这样一个事实,即通过 Eclipse 外部光束计算的 0.5×0.5cm 的输出因子比两者都大 6FFF 和 6MV 束的测量值大 30%以上。
Eclipse 在主准直器尺寸降至 2cm 时表现良好。对于小于 1.5cm 的准直器设置,Eclipse 中的 OF 表应扩展以提高剂量计算精度。